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BID Antibody (40) is a mouse monoclonal IgG1 antibody that detects BID in mouse samples through western blotting (WB) and immunoprecipitation (IP) applications. BID, a crucial member of the Bcl-2 family, plays a significant role in the regulation of apoptosis, acting as a pro-apoptotic factor that can promote cell death in response to various cellular signals. BID′s importance lies in its ability to dimerize with anti-apoptotic proteins like Bcl-2 and Bcl-x, effectively counteracting their protective effects and facilitating the apoptotic process. The presence of a BH3 domain in BID is essential for this dimerization, allowing BID to interact with other proteins in the apoptotic pathway. BID is predominantly localized in the cytosol but can also be found in membrane fractions, highlighting BID′s dynamic role in cellular signaling. BID is highly expressed in the kidney and is also detectable in other tissues such as the brain, spleen, liver, testis, and lung, indicating BID′s widespread influence on cell survival and death across various biological contexts. Anti-BID antibody (40) is an invaluable tool for researchers studying apoptosis and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BID Antibody (40) | sc-135847 | 50 µg/500 µl | $316.00 |