Bicyclomycin is a polar metabolite first isolated from Streptomyces sapporonensis in 1972, with activity against Gram negative bacteria. The selective Gram negative profile of bicyclomycin is rare among Streptomyces metabolites. The benzoate contains a more exposed primary alcohol than its parent compound, bicyclomycin (sc-391755), making it more cell-permeable.
Soluble in ethanol, methanol, DMF, DMSO, and water (Partial).
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
D Heygere et alD Heygere et al. (PubMed ID 25999346) used bicyclomycin (BCM), a rho termination factor inhibitor that binds to a the ATPase subsite in rho, to study bacterial resistance in Mycobacterium tuberculosis. -SCBT Publication Review
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