Date published: 2026-3-18

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(−)-Bicifadine Hydrochloride (CAS 66504-88-9)

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CAS Number:
66504-88-9
Molecular Weight:
209.72
Molecular Formula:
C12H16ClN
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(−)-Bicifadine Hydrochloride is a synthetic compound that belongs to the class of bicyclic amines and functions primarily as a non-opioid analgesic. It is known for its unique dual mechanism of action, which involves the inhibition of the reuptake of both serotonin and norepinephrine, key neurotransmitters in the central nervous system. This inhibition leads to an increase in the synaptic concentrations of these neurotransmitters, which can modulate pain perception by enhancing the descending inhibitory pathways in the spinal cord. Additionally, (−)-Bicifadine has been shown to have weak dopamine reuptake inhibition, which further contributes to its role in altering nociceptive signals. In research settings, (−)-Bicifadine has been employed as a tool to study pain pathways and neurotransmitter interactions, providing insights into the complex mechanisms underlying chronic and acute pain.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(−)-Bicifadine Hydrochloride, 5 mg

sc-210917
5 mg
$360.00