Date published: 2025-12-18

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Bibenzyl (CAS 103-29-7)

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Alternate Names:
1,2-Diphenylethane; Dibenzyl
CAS Number:
103-29-7
Molecular Weight:
182.26
Molecular Formula:
C14H14
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bibenzyl, a member of the benzyl group of molecules, is an organic compound that exists as a white crystalline solid with solubility in various organic solvents. Extensive research has been conducted on bibenzyl to explore its biochemical and physiological effects, as well as its potential for laboratory experiments. In scientific research, bibenzyl has been utilized in various applications, including the study of cell signaling pathways and as a fluorescent dye for imaging purposes. Furthermore, bibenzyl has exhibited agonistic activity towards the G protein-coupled receptor GPR55, a pivotal regulator of cell signaling pathways. This property enables bibenzyl to modulate cellular responses mediated by GPR55.


Bibenzyl (CAS 103-29-7) References

  1. New bibenzyl cannabinoid from the New Zealand liverwort Radula marginata.  |  Toyota, M., et al. 2002. Chem Pharm Bull (Tokyo). 50: 1390-2. PMID: 12372871
  2. [Bibenzyl from Dendrobium inhibits angiogenesis and its underlying mechanism].  |  Gong, CY., et al. 2013. Yao Xue Xue Bao. 48: 337-42. PMID: 23724644
  3. A bibenzyl from Dendrobium ellipsophyllum inhibits migration in lung cancer cells.  |  Chaotham, C. and Chanvorachote, P. 2015. J Nat Med. 69: 565-74. PMID: 26109451
  4. A new flavone C-glycoside and a new bibenzyl from Bulbophyllum retusiusculum.  |  Yang, MH., et al. 2016. Nat Prod Res. 30: 1617-22. PMID: 26729275
  5. Bibenzyl compound 20c protects against endoplasmic reticulum stress in tunicamycin-treated PC12 cells in vitro.  |  Mou, Z., et al. 2016. Acta Pharmacol Sin. 37: 1525-1533. PMID: 27616576
  6. [A new bibenzyl compound from Dendrobium nobile].  |  Xiao, SJ., et al. 2016. Yao Xue Xue Bao. 51: 1117-20. PMID: 29897210
  7. Chemical Constituents and Biological Activity Profiles on Pleione (Orchidaceae).  |  Wu, XQ., et al. 2019. Molecules. 24: PMID: 31484345
  8. Isolation, synthesis, and biological activities of a bibenzyl from Empetrum nigrum var. japonicum.  |  Oka, S., et al. 2020. Biosci Biotechnol Biochem. 84: 31-36. PMID: 31794330
  9. Potential Anti-allergic Effects of Bibenzyl Derivatives from Liverworts, Radula perrottetii.  |  Asai, H., et al. 2022. Planta Med. 88: 1069-1077. PMID: 35081628
  10. Vibrational Spectra and Molecular Vibrational Behaviors of Dibenzyl Disulfide, Dibenzyl Sulphide and Bibenzyl.  |  Wang, Z., et al. 2022. Int J Mol Sci. 23: PMID: 35216075
  11. Atropisomeric 9,10-dihydrophenanthrene/bibenzyl trimers with anti-inflammatory and PTP1B inhibitory activities from Bletilla striata.  |  Sun, M., et al. 2022. Org Biomol Chem. 20: 4736-4745. PMID: 35612380
  12. Characterization of the Key Bibenzyl Synthase in Dendrobium sinense.  |  Chen, Y., et al. 2022. Int J Mol Sci. 23: PMID: 35743224
  13. The inducible 9, 10-dihydrophenanthrene pathway: characterization and expression of bibenzyl synthase and S-adenosylhomocysteine hydrolase.  |  Preisig-Müller, R., et al. 1995. Arch Biochem Biophys. 317: 201-7. PMID: 7872785

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bibenzyl, 25 g

sc-397245
25 g
$48.00