Molecular structure of Betazole Dihydrochloride, CAS Number: 138-92-1
Betazole Dihydrochloride (CAS 138-92-1)
Alternate Names:
1H-Pyrazole-3-ethanamine Dihydrochloride; 3-(2-Aminoethyl)pyrazole Dihydrochloride (6CI,8CI); 3-(2-Aminoethyl)pyrazole Dihydrochloride; 3-(β-Aminoethyl)pyrazole Dihydrochloride; Ametazole Dihydrochloride; Ametazole Hydrochloride; Betazol Hydrochloride; Betazole dihydrochloride; Betazole Hydrochloride; Gastramine; Gastramine Hydrochloride; Histalog
CAS Number:
138-92-1
Molecular Weight:
184.07
Molecular Formula:
C5H11Cl2N3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Betazole dihydrochloride is a histamine H2 receptor agonist. It is used as a gastric stimulant for the investigation of gastric secretion activity. It helps to evaluate the functionality of the stomach cells that produce acid. Its action mimics that of histamine, a naturally occurring compound in the body known for its role in immune responses, gastric acid secretion, and as a neurotransmitter. Betazole dihydrochloride′s role as a research tool extends into the study of histamine receptors and their functions. By selectively activating the H2 receptors, it allows scientists to explore the physiological roles of these receptors in various tissues.
Betazole Dihydrochloride (CAS 138-92-1) References
- [Effect of somatostatin on betazole-stimulated gastric secretion and carbachol-stimulated pancreatic secretion and gall bladder contraction in man(author's transl)]. | Lankisch, PG., et al. 1975. Dtsch Med Wochenschr. 100: 1797-800. PMID: 1157680
- A simple oral gastric secretory stimulant (betazole hydrochloride). | CLAYMAN, CB., et al. 1961. JAMA. 175: 908-9. PMID: 14448724
- Cyclic adenosine monophosphate and human gastric acid secretion. | Bower, RH., et al. 1977. Am J Dig Dis. 22: 705-11. PMID: 195465
- Synthesis and Pharmacological Activities of Pyrazole Derivatives: A Review. | Karrouchi, K., et al. 2018. Molecules. 23: PMID: 29329257
- Effects of cyclic nucleotides, betazole hydrochloride and acetylcholine on pepsinogen secretion from isolated rabbit gastric mucosa. | Noguchi, Y., et al. 1986. Gastroenterol Jpn. 21: 129-34. PMID: 3011576
- Biocatalytic access to betazole using a one-pot multienzymatic system in continuous flow. | Romero-Fernandez, M. and Paradisi, F. 2021. Green Chem. 23: 4594-4603. PMID: 34220333
- Inhibitory effect of bromazepam on basal and betazole-stimulated gastric acid secretion in man. | Stacher, G. and Stärker, D. 1974. Gut. 15: 116-20. PMID: 4820635
- Toxicity of betazole hydrochloride for the pertussis-sensitized mouse. | Malkiel, S. and Hargis, BJ. 1966. Proc Soc Exp Biol Med. 122: 685-6. PMID: 5918933
- [The use of betazole hydrochloride (Histalog) in the study of gastric secretion]. | Dal Monte, PR., et al. 1966. G Clin Med. 47: 865-72. PMID: 5994052
- Betazole-induced GIP secretion is not mediated by gastric HCl. | Spitz, IM., et al. 1982. Metabolism. 31: 380-2. PMID: 7078422
- Effects of betazole hydrochloride and cimetidine on common bile pressure and duodenal myoelectric activity in the dog. | Maples, MD., et al. 1981. Am Surg. 47: 519-21. PMID: 7316286
- Comparison of dose-response curves between acid and pepsin to betazole hydrochloride in the dog with gastric fistula. | Ishimori, A., et al. 1975. Gastroenterol Jpn. 10: 221-4. PMID: 789169
- Effect of betazole on serum group I pepsinogen levels: relationship to gastric acid output in unoperated and postoperative patients. | Samloff, IM., et al. 1977. Gastroenterology. 72: 845-8. PMID: 849814
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Betazole Dihydrochloride, 2.5 mg | sc-503471 | 2.5 mg | $350.00 |