Betanin (CAS 7659-95-2)
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Betanin, also referred to as E162 or phytolaccanin, is classified as a betacyanin and derivative compound. Betacyanins are organic compounds that feature a glycoside of indolium-2-carboxylic acid attached, with the nitrogen ring of the indolium ring connected to a derivative of ethylpyridine-2,6-dicarboxylic acid. These red nitrogenous pigments are naturally present in certain plants, including beetroots. Betanin itself is considered to be relatively neutral and exhibits low solubility in water. Its primary cellular location is in the cytoplasm. Beyond the human body, betanin can be found in various food items such as agar, acorn, endive, and mandarin orange (clementine, tangerine). Consequently, betanin holds the potential to serve as a biomarker for the consumption of these specific food products.
Betanin (CAS 7659-95-2) References
- Betanin--a food colorant with biological activity. | Esatbeyoglu, T., et al. 2015. Mol Nutr Food Res. 59: 36-47. PMID: 25178819
- Metabolic engineering of rice endosperm for betanin biosynthesis. | Tian, YS., et al. 2020. New Phytol. 225: 1915-1922. PMID: 31737907
- Effect of Betanin, a Beetroot Component, on Vascular Tone in Isolated Porcine Arteries. | Tawa, M., et al. 2020. Am J Hypertens. 33: 305-309. PMID: 31913440
- The protective effect of betanin and copper on spinal cord ischemia-reperfusion injury. | Tural, K., et al. 2021. J Spinal Cord Med. 44: 704-710. PMID: 32223592
- Betanin purification from red beetroots and evaluation of its anti-oxidant and anti-inflammatory activity on LPS-activated microglial cells. | Ahmadi, H., et al. 2020. PLoS One. 15: e0233088. PMID: 32401824
- The neuroprotective effect of betanin in trimethyltin-induced neurodegeneration in mice. | Thong-Asa, W., et al. 2020. Metab Brain Dis. 35: 1395-1405. PMID: 32894390
- Betanin as a multipath oxidative stress and inflammation modulator: a beetroot pigment with protective effects on cardiovascular disease pathogenesis. | Silva, DVTD., et al. 2022. Crit Rev Food Sci Nutr. 62: 539-554. PMID: 32997545
- Betanin Prevents Experimental Abdominal Aortic Aneurysm Progression by Modulating the TLR4/NF-κB and Nrf2/HO-1 Pathways. | Qiu, R., et al. 2021. Biol Pharm Bull. 44: 1254-1262. PMID: 34471054
- Betanin Dose-Dependently Ameliorates Allergic Airway Inflammation by Attenuating Th2 Response and Upregulating cAMP-PKA-CREB Pathway in Asthmatic Mice. | Li, Q., et al. 2022. J Agric Food Chem. 70: 3708-3718. PMID: 35298142
- Betanin alleviates inflammation and ameliorates apoptosis on human oral squamous cancer cells SCC131 and SCC4 through the NF-κB/PI3K/Akt signaling pathway. | Zou, X., et al. 2022. J Biochem Mol Toxicol. 36: e23094. PMID: 35645143
- Effects of Betanin on Pasting, Rheology and Retrogradation Properties of Different Starches. | Dai, T., et al. 2022. Foods. 11: PMID: 35681351
- Evaluation of three methods for betanin quantification in fruits from cacti. | Sandate-Flores, L., et al. 2022. MethodsX. 9: 101746. PMID: 35707638
- Betanin alleviates oxidative stress through the Nrf2 signaling pathway in the liver of STZ-induced diabetic rats. | Mousavi, M., et al. 2022. Mol Biol Rep. 49: 9345-9354. PMID: 35988103
- Betanin ameliorates fipronil-induced nephrotoxicity via activation of Nrf2-HO-1/NQO-1 pathway in albino rat model. | Sakr, S., et al. 2022. Toxicol Res (Camb). 11: 975-986. PMID: 36569480
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Betanin, 25 g | sc-486141 | 25 g | $114.00 | |||
Betanin, 100 g | sc-486141A | 100 g | $322.00 |