Betamethasone-d5 (CAS 378-44-9 unlabeled)
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Betamethasone-d5 is a deuterated analog of betamethasone, where five hydrogen atoms are replaced by deuterium, a stable isotope of hydrogen. This analog is primarily used in analytical research to study the kinetics and metabolic pathways of betamethasone. Deuterated compounds like betamethasone-d5 are often employed as internal standards in mass spectrometry because they closely mimic the behavior of the non-deuterated compound while allowing for differentiation based on the mass difference introduced by deuterium. Researchers utilize betamethasone-d5 to precisely quantify the parent compound in biological samples, ensuring accurate and reliable data. In addition to its role in analytical techniques, it can also be used to investigate the mechanism of chemical action and distribution within biological systems without the interference from endogenous compounds.
Betamethasone-d5 (CAS 378-44-9 unlabeled) References
- Development and validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous determination of nine corticosteroid residues in bovine liver samples. | Dusi, G., et al. 2011. Anal Chim Acta. 700: 49-57. PMID: 21742116
- Positive doping results caused by the single-dose local injection of triamcinolone acetonide. | Chang, CW., et al. 2014. Forensic Sci Int. 244: 1-6. PMID: 25126738
- Elimination profile of triamcinolone in urine following oral administration. | Chen, TT., et al. 2018. Drug Test Anal. 10: 860-864. PMID: 29155490
- Transcriptome Analysis of Orbital Adipose Tissue in Active Thyroid Eye Disease Using Next Generation RNA Sequencing Technology. | Lee, BW., et al. 2018. Open Ophthalmol J. 12: 41-52. PMID: 29760827
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Betamethasone-d5, 1 mg | sc-217751 | 1 mg | $660.00 |