Date published: 2025-9-5

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Betamethasone 21-phosphate sodium salt (CAS 151-73-5)

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Alternate Names:
Bentelan
Application:
Betamethasone 21-phosphate sodium salt is an anti-inflammatory agent
CAS Number:
151-73-5
Molecular Weight:
516.40
Molecular Formula:
C22H28FNa2O8P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Betamethasone 21-phosphate sodium salt is a corticosteroid that functions as an anti-inflammatory agent in experimental applications. It exerts its mechanism of action by binding to intracellular glucocorticoid receptors, leading to the upregulation of anti-inflammatory genes and the downregulation of pro-inflammatory genes. This results in the suppression of the immune response and the reduction of inflammation at the molecular level. Betamethasone 21-phosphate sodium salt inhibits the production of inflammatory mediators, such as prostaglandins and leukotrienes, by interfering with the arachidonic acid pathway. It modulates the activity of transcription factors involved in the inflammatory response, thereby exerting its anti-inflammatory effects at the cellular level.


Betamethasone 21-phosphate sodium salt (CAS 151-73-5) References

  1. Stabilization and HPLC analysis of betamethasone sodium phosphate in plasma.  |  Samtani, MN., et al. 2004. J Pharm Sci. 93: 726-32. PMID: 14762910
  2. Betamethasone sodium phosphate.  |  . Nurs Times. 100: 43. PMID: 15630973
  3. Efficacy and systemic tolerability of mometasone furoate and betamethasone sodium phosphate.  |  Patel, RS., et al. 2004. J Laryngol Otol. 118: 866-71. PMID: 15638973
  4. Forced degradation of betamethasone sodium phosphate under solid state: Formation, characterization, and mechanistic study of all four 17,20-diastereomers of betamethasone 17-deoxy-20-hydroxy-21-oic acid.  |  Li, M., et al. 2009. J Pharm Sci. 98: 894-904. PMID: 18623204
  5. Development and validation of a discriminative dissolution test for betamethasone sodium phosphate and betamethasone dipropionate intramuscular injectable suspension.  |  Simon, A., et al. 2013. AAPS PharmSciTech. 14: 425-34. PMID: 23371786
  6. Annoying Hiccups following Intra-Articular Corticosteroid Injection of Betamethasone Acetate/Betamethasone Sodium Phosphate at the Knee Joint.  |  Habib, G., et al. 2013. Case Rep Rheumatol. 2013: 829620. PMID: 23573452
  7. The effect of intra-articular injection of betamethasone acetate/betamethasone sodium phosphate at the knee joint on the hypothalamic-pituitary-adrenal axis: a case-controlled study.  |  Habib, G., et al. 2013. J Investig Med. 61: 1104-7. PMID: 24013525
  8. Pharmacokinetics of intra-articular betamethasone sodium phosphate and betamethasone acetate and endogenous hydrocortisone suppression in exercising horses.  |  Menendez, MI., et al. 2016. J Vet Pharmacol Ther. 39: 22-6. PMID: 25847081
  9. Quantitative determination of betamethasone sodium phosphate and betamethasone dipropionate in human plasma by UPLC-MS/MS and a bioequivalence study.  |  Chen, MY., et al. 2016. Anal Methods. 8: 3550-3563. PMID: 27695531
  10. Sensitization/tolerance profile of betamethasone sodium phosphate in patients with contact allergy to budesonide.  |  Hansel, K., et al. 2020. Dermatol Ther. 33: e14155. PMID: 32770695
  11. Non-Particulate Steroids (Betamethasone Sodium Phosphate, Dexamethasone Sodium Phosphate, and Dexamethasone Palmitate) Combined with Local Anesthetics (Ropivacaine, Levobupivacaine, Bupivacaine, and Lidocaine): A Potentially Unsafe Mixture.  |  Choi, EJ., et al. 2021. J Pain Res. 14: 1495-1504. PMID: 34079364
  12. M2-type exosomes nanoparticles for rheumatoid arthritis therapy via macrophage re-polarization.  |  Li, H., et al. 2022. J Control Release. 341: 16-30. PMID: 34793917
  13. A Comparative Study of the Respiratory Neonatal Outcomes Utilizing Dexamethasone Sodium Phosphate versus a Mixture of Betamethasone Dipropionate and Betamethasone Sodium Phosphate as an Antenatal Corticosteroid Therapy.  |  Altal, OF., et al. 2021. Int J Gen Med. 14: 9471-9481. PMID: 34949936
  14. Stability of betamethasone sodium phosphate, hydrocortisone sodium phosphate, and prednisolone sodium phosphate injections submitted by U.S. hospitals.  |  Kreienbaum, MA. 1986. Am J Hosp Pharm. 43: 1747-50. PMID: 3752113

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Betamethasone 21-phosphate sodium salt, 250 mg

sc-204648
250 mg
$115.00

Betamethasone 21-phosphate sodium salt, 1 g

sc-204648A
1 g
$351.00