Date published: 2026-5-5

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Betahistine Hydrochloride (CAS 15430-48-5)

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Alternate Names:
Serc; Veserc
Application:
Betahistine Hydrochloride is a histamine analog and H1 receptor agonist
CAS Number:
15430-48-5
Molecular Weight:
172.66
Molecular Formula:
C8H13ClN2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Betahistine Hydrochloride (CAS 15430-48-5) References

  1. Utilization of carbon disulphide for the analytical determination of betahistine hydrochloride and captopril in their pharmaceutical preparations.  |  El Walily, AF., et al. 1999. J Pharm Biomed Anal. 21: 439-49. PMID: 10704001
  2. Lack of substantial effect of the H(3)-antagonist thioperamide and of the non-selective mixed H(3)-antagonist/H(1)-agonist betahistine on amygdaloid kindled seizures.  |  Yoshida, M., et al. 2000. Epilepsy Res. 40: 141-5. PMID: 10863141
  3. Binding affinity profile of betahistine and its metabolites for central histamine receptors of rodents.  |  Fossati, A., et al. 2001. Pharmacol Res. 43: 389-92. PMID: 11352543
  4. Stress degradation studies on betahistine and development of a validated stability-indicating assay method.  |  Khedr, A. and Sheha, M. 2008. J Chromatogr B Analyt Technol Biomed Life Sci. 869: 111-7. PMID: 18524698
  5. Spectrophotometric estimation of betahistine hydrochloride in tablet formulations.  |  Kumar, A., et al. 2010. J Pharm Bioallied Sci. 2: 121-3. PMID: 21814445
  6. Topical application of betahistine improves eustachian tube function in an animal model.  |  Franz, B., et al. 2011. Acta Otolaryngol. 131: 1155-9. PMID: 21905792
  7. Development and evaluation of sustained release tablet of betahistine hydrochloride using ion exchange resin tulsion t344.  |  Wagh, VD. and Pawar, N. 2012. ISRN Pharm. 2012: 438342. PMID: 22779010
  8. Transdermal delivery of betahistine hydrochloride using microemulsions: physical characterization, biophysical assessment, confocal imaging and permeation studies.  |  Hathout, RM. and Nasr, M. 2013. Colloids Surf B Biointerfaces. 110: 254-60. PMID: 23732802
  9. Effect of drug-ion exchange resin complex in betahistine hydrochloride orodispersible film on sustained release, taste masking and hygroscopicity reduction.  |  Shang, R., et al. 2018. Int J Pharm. 545: 163-169. PMID: 29729403
  10. Modulation of inner filter effect of non-conjugated silver nanoparticles on blue emitting ZnS quantum dots for the quantitation of betahistine.  |  Chavada, VD., et al. 2020. Spectrochim Acta A Mol Biomol Spectrosc. 240: 118575. PMID: 32534429
  11. A Review on Spike and Recovery Method in Analytical Method Development and Validation.  |  Thakur, D., et al. 2022. Crit Rev Anal Chem. 1-19. PMID: 36463526
  12. The effect of Serc (betahistine hydrochloride) on the circulation of the inner ear in experimental animals.  |  Martinez, DM. 1972. Acta Otolaryngol Suppl. 305: 29-47. PMID: 4353749
  13. The effects of betahistine on the isolated perfused baboon kidney.  |  Groenewald, JH., et al. 1970. S Afr Med J. 44: 1002-5. PMID: 4990314
  14. Effects of betahistine HCl, nicotinic acid, and histamine on basilar blood flow in anesthetized dogs.  |  Anderson, WD. and Kubicek, WG. 1971. Stroke. 2: 409-15. PMID: 5000331

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Betahistine Hydrochloride, 50 mg

sc-210906
50 mg
$2290.00