Date published: 2025-9-21

1-800-457-3801

SCBT Portrait Logo
Seach Input

β3 Tubulin Antibody (AA10): sc-80016

4.9(9)
Write a reviewAsk a question

Datasheets
  • β3 Tubulin Antibody (AA10) is a mouse monoclonal IgG2a κ, cited in 36 publications, provided at 200 µg/ml
  • raised against β3 Tubulin of rat origin, with epitope mapping to amino acids 436-450
  • Anti-beta 3 Tubulin Antibody (AA10) is recommended for detection of β3 Tubulin of mouse, rat and human origin by WB, IP and IF
  • Anti-beta 3 Tubulin Antibody (AA10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
  • Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of β3 Tubulin (AA10): sc-80016.
  • m-IgG2a BP-HRP is the preferred secondary detection reagent for β3 Tubulin Antibody (AA10) for WB applications. This reagent is now offered in a bundle with β3 Tubulin Antibody (AA10) (see ordering information below).

QUICK LINKS

SEE ALSO...

β3 Tubulin Antibody (AA10) is a mouse monoclonal IgG2a kappa light chain antibody that detects β3 Tubulin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). anti-β3 Tubulin antibody (AA10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. β3 Tubulin is a neuron-specific cytoskeletal protein that plays a crucial role in the formation and stabilization of microtubules, which are essential for maintaining cell shape, intracellular transport, and the proper functioning of neuronal processes. The unique expression of β3 Tubulin in neurons, as opposed to other β Tubulin isoforms, highlights its importance in neurodevelopment and the maintenance of neuronal integrity. β3 Tubulin interacts with various proteins, including MAP2 and Tau, which are vital for microtubule stabilization and neuronal signaling. Understanding the interactions and functions of β3 Tubulin is critical for elucidating the mechanisms underlying neurodegenerative diseases and neuronal injuries, making β3 Tubulin (AA10) monoclonal antibody an invaluable tool for researchers studying the nervous system.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

β3 Tubulin Antibody (AA10)

sc-80016
200 µg/ml
$316.00

β3 Tubulin Antibody (AA10): m-IgG2a BP-HRP Bundle

sc-545917
200 µg Ab; 10 µg BP
$354.00

β3 Tubulin Antibody (AA10) AC

sc-80016 AC
500 µg/ml, 25% agarose
$416.00

β3 Tubulin Antibody (AA10) HRP

sc-80016 HRP
200 µg/ml
$316.00

β3 Tubulin Antibody (AA10) FITC

sc-80016 FITC
200 µg/ml
$330.00

β3 Tubulin Antibody (AA10) PE

sc-80016 PE
200 µg/ml
$343.00

β3 Tubulin Antibody (AA10) Alexa Fluor® 488

sc-80016 AF488
200 µg/ml
$357.00

β3 Tubulin Antibody (AA10) Alexa Fluor® 546

sc-80016 AF546
200 µg/ml
$357.00

β3 Tubulin Antibody (AA10) Alexa Fluor® 594

sc-80016 AF594
200 µg/ml
$357.00

β3 Tubulin Antibody (AA10) Alexa Fluor® 647

sc-80016 AF647
200 µg/ml
$357.00

β3 Tubulin Antibody (AA10) Alexa Fluor® 680

sc-80016 AF680
200 µg/ml
$357.00

β3 Tubulin Antibody (AA10) Alexa Fluor® 790

sc-80016 AF790
200 µg/ml
$357.00

I need to use an antibody to detect the protein in samples of porcine origin. Do you know if this mouse monoclonal antibody will work?

Asked by: jerojero
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Tech Service 3
Date published: 2017-02-01
  • y_2025, m_9, d_17, h_8CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_80016, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 105ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Great signalStrong signal, no background, band at 55 KDa. Tested in mouse hippocampal lysates and rat primary cultured neurons (1:500 in 5% nonfat dry milk-TBS-Tween).
Date published: 2023-04-07
Rated 5 out of 5 by from Great signalStrong signal, no background, band at 55 KDa. Tested in mouse hippocampal lysates and rat primary cultured neurons (1:500 in 5% nonfat dry milk-TBS-Tween).
Date published: 2023-04-04
Rated 5 out of 5 by from Great signalStrong signal, no background, band at 55 KDa. Tested in mouse hippocampal lysates and rat primary cultured neurons (1:500 in 5% nonfat dry milk-TBS-Tween).
Date published: 2023-04-04
Rated 5 out of 5 by from Great signalStrong signal, no background, band at 55 KDa. Tested in mouse hippocampal lysates and rat primary cultured neurons (1:500 in 5% nonfat dry milk-TBS-Tween).
Date published: 2023-04-04
Rated 5 out of 5 by from Excelent antibodyStrong signal, no background, band at 55 KDa. Tested in mouse hippocampal lysates and rat primary cultured neurons (1:500 in 5% nonfat dry milk-TBS-Tween).
Date published: 2023-04-04
Rated 4 out of 5 by from Melanocortin 4 receptor activation protects striatα-Melanocyte stimulating hormone (α-MSH) is a melanocortin which exerts potent anti-inflammatory and antiapoptotic effects. Melanocortin 4 receptors (MC4R) are abundantly expressed in the brain and we previously demonstrated that [Nle(4), D-Phe(7)]melanocyte-stimulating hormone (NDP-MSH), an α-MSH analogue, increased expression of brain derived-neurotrophic factor (BDNF), and peroxisome proliferator-activated receptor- γ (PPAR-γ). We hypothesized that melanocortins could affect striatal cell survival through BDNF and PPAR-γ. First, we determined the expression of these factors in the striatum. Acute intraperitoneal administration (0.5 mg/kg) of α-MSH increased the levels of BDNF mRNA in rat striatum but not in rat cerebral cortex. Also, protein expression of PPAR-γ and MC4R was increased by acute treatment with α-MSH in striatum but not in cortex. No changes were observed by 48 h treatment. Next, we evaluated melanocortins effect on neuron and glial survival. 3-nitropropionic acid (3-NP), which is known to induce striatal degeneration, was used to induce cell death in the rat striatal cell line ST14A expressing mutant human huntingtin (Q120) or in ST14A cells expressing normal human huntingtin (Q15), in primary cultured astrocytes, and in BV2 cells. NDP-MSH protected Q15 cells, astrocytes and BV2 cells from death by 3-NP whereas it did not fully protect Q120 cells. Protection of Q15 cells and astrocytes was blocked by a MC4R specific inhibitor (JKC-363) and a PPAR-γ antagonist (GW9662). The BDNF receptor antagonist (ANA-12) abolished NDP-MSH protective effect in astrocytes but not in Q15 cells. We demonstrate for the first time that melanocortins, acting through PPAR-γ and BDNF, protect neurons and glial cells from 3-NP toxicity
Date published: 2018-12-13
Rated 5 out of 5 by from Very good resultbeta-3-tubulin antibody (AA10) sc-800166: Immunofluorescence staining of beta-3-tubulin (green) and S100 (red) in rat dorsal root ganglion fixed in 4% paraformaldehyde.
Date published: 2018-02-06
Rated 5 out of 5 by from Produced good western blot bandThe tubulin antibody produced a clear western blot band for our cell lysate
Date published: 2016-12-20
  • y_2025, m_9, d_17, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_9
  • loc_en_US, sid_80016, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 15ms
  • REVIEWS, PRODUCT
β3 Tubulin Antibody (AA10) is rated 4.9 out of 5 by 9.
  • y_2025, m_9, d_17, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_9
  • loc_en_US, sid_80016, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 112ms
  • REVIEWS, PRODUCT