β2A Tubulin Antibody (2-RY22): sc-134229

β2A Tubulin Antibody (2-RY22) is a mouse monoclonal IgG2a kappa light chain antibody that detects β2A Tubulin of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). anti-β2A Tubulin antibody (2-RY22) is available in a non-conjugated form, specifically designed for researchers seeking to study the dynamics of microtubule formation and function. β2A Tubulin, also known as TUBB2A, is a crucial component of the cytoskeleton, existing as a heterodimer with α-tubulin to form microtubules that provide structural support and facilitate intracellular transport. β2A Tubulin plays a significant role in maintaining cell shape, enabling cell division, and facilitating the movement of organelles within cells. β2A Tubulin is involved in various cellular processes, including mitosis and the stabilization of microtubule structures, which are essential for proper cellular function and organization. The presence of multiple β-tubulin isoforms, including β2A, allows for functional diversity and adaptability in response to cellular needs, making β2A Tubulin a vital area of study in understanding cytoskeletal dynamics and their implications in health and disease.

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β2A Tubulin Antibody (2-RY22) References:

1. Presence of the betaII isotype of tubulin in the nuclei of cultured mesangial cells from rat kidney.  |  Walss, C., et al. 1999. Cell Motil Cytoskeleton. 42: 274-84. PMID: 10223634
2. Genetic analysis of the beta-tubulin gene, TUBB, in non-small-cell lung cancer.  |  Kelley, MJ., et al. 2001. J Natl Cancer Inst. 93: 1886-8. PMID: 11752014
3. Re: genetic analysis of the beta-tubulin gene, TUBB, in non-small-cell lung cancer.  |  Sale, S., et al. 2002. J Natl Cancer Inst. 94: 776-7; author reply 777. PMID: 12011233
4. Alpha-, beta-, and gamma-tubulins: sequence comparisons and structural constraints.  |  Burns, RG. 1991. Cell Motil Cytoskeleton. 20: 181-9. PMID: 1773446
5. Beta-tubulin isotype classes II and V expression patterns in nonsmall cell lung carcinomas.  |  Cucchiarelli, V., et al. 2008. Cell Motil Cytoskeleton. 65: 675-85. PMID: 18613117
6. The effects of acute 17beta-estradiol treatment on gene expression in the young female mouse hippocampus.  |  Pechenino, AS. and Frick, KM. 2009. Neurobiol Learn Mem. 91: 315-22. PMID: 18938255
7. Evolutionary history of a multigene family: an expressed human beta-tubulin gene and three processed pseudogenes.  |  Lee, MG., et al. 1983. Cell. 33: 477-87. PMID: 6688039
8. Multiple forms of tubulin: different gene products and covalent modifications.  |  Ludueña, RF. 1998. Int Rev Cytol. 178: 207-75. PMID: 9348671
9. Expression of amino- and carboxyl-terminal gamma- and alpha-tubulin mutants in cultured epithelial cells.  |  Leask, A. and Stearns, T. 1998. J Biol Chem. 273: 2661-8. PMID: 9446570

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-β2A Tubulin Antibody (2-RY22) has 5 citations in a variety of scientific publications.

Primary antibodies like Anti-β2A Tubulin Antibody (2-RY22) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

β2A Tubulin Antibody (2-RY22) Specifications

Alternate Product Name: beta tubulin 2A

Product Clone Name: 2-RY22

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 1-446

Epitope Target: β2ATubulin

Epitope Species: human

Product Reactivity/Detection: β2A Tubulin

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 5 citations in various scientific publications

Available Conjugates/Forms for β2A Tubulin Antibody (2-RY22): N/A