beta Tubulin Antibody (SAP.4G5): sc-58884

β Tubulin Antibody (SAP.4G5) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect β Tubulin, also known as tubulin beta chain, across a wide range of species including mouse, rat, human, Xenopus, avian, bovine, and canine. β Tubulin monoclonal antibody (SAP.4G5) is raised against the C-terminus of β Tubulin isotype I of chicken origin, ensuring robust and precise binding in applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). β Tubulin is a pivotal component of the cytoskeleton, forming heterodimers with α Tubulin that assemble into microtubules, which are essential for maintaining cell shape, facilitating intracellular transport, and enabling accurate cell division. β Tubulin interacts with a variety of proteins, including motor proteins like kinesin and dynein, which traverse microtubules to transport cellular cargo, and microtubule-associated proteins (MAPs) such as MAP1 and MAP2 that regulate microtubule stability and dynamics. These interactions are crucial for processes such as vesicle trafficking, organelle positioning, and the establishment of cell polarity. Additionally, β Tubulin serves as a binding site for various drugs and regulatory proteins, making β Tubulin a key target in research areas like neurobiology, cancer, and developmental biology. Understanding β Tubulin interactions with these proteins provides valuable insights into the mechanisms of cellular organization and the progression of diseases involving cytoskeletal dysfunction. Anti-β Tubulin antibody (SAP.4G5) is available in both non-conjugated forms and various conjugated forms, including horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, offering versatility for diverse experimental needs.

The preferred beta Tubulin antibody is beta Tubulin Antibody (D-10): sc-5274.