Date published: 2026-4-21

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β-Pseudouridine (CAS 1445-07-4)

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Alternate Names:
5-β-D-Ribofuranosyluracil; Pseudouridine
Application:
β-Pseudouridine is a compound also known as 5-β-D-Ribofuranosylpyrimidine-2,4(1H,3H)-dione
CAS Number:
1445-07-4
Purity:
≥97%
Molecular Weight:
244.20
Molecular Formula:
C9H12N2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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β-Pseudouridine is a compound also known as 5-beta-D-Ribofuranosylpyrimidine-2,4(1H,3H)-dione. It is used to study tRNA interactions with aminoacyl transferases. May also protect from radiation.


β-Pseudouridine (CAS 1445-07-4) References

  1. Beta-pseudouridine, a beer component, reduces radiation-induced chromosome aberrations in human lymphocytes.  |  Monobe, M., et al. 2003. Mutat Res. 538: 93-9. PMID: 12834758
  2. Simultaneous high performance liquid chromatographic separation of purines, pyrimidines, N-acetylated amino acids, and dicarboxylic acids for the chemical diagnosis of inborn errors of metabolism.  |  Tavazzi, B., et al. 2005. Clin Biochem. 38: 997-1008. PMID: 16139832
  3. Structure-based organic synthesis of drug prototypes: a personal odyssey.  |  Hanessian, S. 2006. ChemMedChem. 1: 1301-30. PMID: 17091524
  4. Effects of glycine betaine on bone marrow death and intestinal damage by gamma rays and carbon ions.  |  Monobe, M., et al. 2006. Radiat Prot Dosimetry. 122: 494-7. PMID: 17145728
  5. Recent insights into the biological action of heavy-ion radiation.  |  Hamada, N. 2009. J Radiat Res. 50: 1-9. PMID: 18838844
  6. Serum metabolic profile in multiple sclerosis patients.  |  Tavazzi, B., et al. 2011. Mult Scler Int. 2011: 167156. PMID: 22096628
  7. Serum Compounds of Energy Metabolism Impairment Are Related to Disability, Disease Course and Neuroimaging in Multiple Sclerosis.  |  Lazzarino, G., et al. 2017. Mol Neurobiol. 54: 7520-7533. PMID: 27826747
  8. Gas Chromatography-Mass Spectrometry for Metabolite Profiling of Japanese Black Cattle Naturally Contaminated with Zearalenone and Sterigmatocystin.  |  Toda, K., et al. 2017. Toxins (Basel). 9: PMID: 28934162
  9. Validation of a Metabolite Panel for a More Accurate Estimation of Glomerular Filtration Rate Using Quantitative LC-MS/MS.  |  Freed, TA., et al. 2019. Clin Chem. 65: 406-418. PMID: 30647123
  10. Drinking Behavior, Taste Preferences and Special Beer Perception among Romanian University Students: A Qualitative Assessment Research.  |  Jimborean, MA., et al. 2021. Int J Environ Res Public Health. 18: PMID: 33806851
  11. Plasma metabolomics provides new insights into the relationship between metabolites and outcomes and left ventricular remodeling of coronary artery disease.  |  Zhu, Q., et al. 2022. Cell Biosci. 12: 173. PMID: 36242008
  12. Combined Transcriptome and Metabolome Profiling Provide Insights into Cold Responses in Rapeseed (Brassica napus L.) Genotypes with Contrasting Cold-Stress Sensitivity.  |  Liu, X., et al. 2022. Int J Mol Sci. 23: PMID: 36362332
  13. Structural and dynamic effects of pseudouridine modifications on non-canonical interactions in RNA.  |  Voegele, J., et al. 2023. RNA.. PMID: 36868785
  14. A nuclear magnetic resonance study of the molecular conformation of beta-pseudouridine in aqueous solution.  |  Hruska, FE., et al. 1970. J Am Chem Soc. 92: 4088-94. PMID: 5419047
  15. Structure and conformation of pseudouridine analogues.  |  Lipnick, RL., et al. 1981. Biochemistry. 20: 7319-27. PMID: 7317385

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

β-Pseudouridine, 10 mg

sc-291984
10 mg
$161.00

β-Pseudouridine, 50 mg

sc-291984A
50 mg
$213.00

β-Pseudouridine, 100 mg

sc-291984B
100 mg
$369.00

β-Pseudouridine, 250 mg

sc-291984C
250 mg
$785.00

β-Pseudouridine, 500 mg

sc-291984D
500 mg
$1254.00

What's the general purity of a lot? I think you might have this if i request a certificate of anlysis for a lot I buy, but I want to know the standard purity before buying.

Asked by: Justin1
Thank you for your question. The purity varies between lot to lot, but recent lots have had 100% purity. Please contact Technical Service by phone, (800)-457-3801 option 2, email <scbt@scbt.com>, or by live chat directly on our website, www.scbt.com if you have any further questions.
Answered by: Tech Service
Date published: 2017-06-20
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Rated 5 out of 5 by from Various publications cite the use of PseudouridineVarious publications cite the use of Pseudouridine ( -Pseudouridine) to study tRNA interactions with aminoacyl transderases. -SCBT Publication Review
Date published: 2015-01-31
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β-Pseudouridine is rated 5.0 out of 5 by 1.
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