β-Nicotinamide adenine dinucleotide 3′-phosphate reduced form, sodium salt

β-Nicotinamide adenine dinucleotide 3′-phosphate reduced form, sodium salt is a coenzyme involved in various metabolic processes. It is found in the vitamin niacin (nicotinamide) and plays a vital role in cellular energy production and redox reactions. This chemical compound, abbreviated as NADPH, exists as a sodium salt and is present in both prokaryotic and eukaryotic cells. NADPH acts as a reducing agent, providing the necessary reducing equivalents for numerous enzymatic reactions, including those involved in biosynthesis, antioxidant defense mechanisms, and detoxification processes. Due to its pivotal role in cellular metabolism, NADPH has garnered significant attention in scientific research. It has been extensively studied in fields such as biochemistry and molecular biology. NADPH serves as an essential cofactor for various enzymes, particularly those involved in redox reactions. It acts as an electron donor, aiding in the conversion of substrates and facilitating critical biochemical transformations. Additionally, NADPH contributes to the maintenance of cellular redox homeostasis, playing a vital role in the defense against oxidative stress and the regeneration of antioxidant molecules. Moreover, NADPH plays a significant role in biosynthetic processes, providing the reducing power required for the synthesis of lipids, nucleotides, and other essential cellular components. It also participates in detoxification reactions, aiding in the metabolism and elimination of toxins and xenobiotics from the body. β-Nicotinamide adenine dinucleotide 3′-phosphate reduced form, sodium salt may also be used as an inhibitory analogue to study the specificity and kinetics of NADP+/NADPH-dependent enzymes. 3′-NADPH is used to study copper ion aggregation of prion protein.