Molecular structure of β-Methyl Digoxin, CAS Number: 30685-43-9
β-Methyl Digoxin (CAS 30685-43-9)
Application:
β-Methyl Digoxin is a cardiotonic methylated digoxin derivative
CAS Number:
30685-43-9
Purity:
96%
Molecular Weight:
794.97
Molecular Formula:
C42H66O14
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
β-Methyl Digoxin is a cardiotonic and obtained by the O-methylation of Digoxin.
β-Methyl Digoxin (CAS 30685-43-9) References
- The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin. | Greiner, B., et al. 1999. J Clin Invest. 104: 147-53. PMID: 10411543
- High-performance liquid chromatography assay of amiodarone in rat plasma. | Jun, AS. and Brocks, DR. 2001. J Pharm Pharm Sci. 4: 263-8. PMID: 11737993
- Effect of 17 beta-estradiol-D-17 beta-glucuronide on the rat organic anion transporting polypeptide 2-mediated transport differs depending on substrates. | Sugiyama, D., et al. 2002. Drug Metab Dispos. 30: 220-3. PMID: 11792694
- A new semisynthetic cardenolide analog 3β-[2-(1-amantadine)- 1-on-ethylamine]-digitoxigenin (AMANTADIG) affects G2/M cell cycle arrest and miRNA expression profiles and enhances proapoptotic survivin-2B expression in renal cell carcinoma cell lines. | Nolte, E., et al. 2017. Oncotarget. 8: 11676-11691. PMID: 28099931
- Age-related changes in Na, K-ATPase expression, subunit isoform selection and assembly in the stria vascularis lateral wall of mouse cochlea. | Ding, B., et al. 2018. Hear Res. 367: 59-73. PMID: 30029086
- Cellular basis for the species differences in sensitivity to cardiac glycosides (digitalis). | Gupta, RS., et al. 1986. J Cell Physiol. 127: 197-206. PMID: 3009493
- Cardiotonic steroids as potential Na+/K+-ATPase inhibitors - a computational study. | Patel, CN., et al. 2019. J Recept Signal Transduct Res. 39: 226-234. PMID: 31509043
- Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators. | Hunter, J., et al. 1993. J Biol Chem. 268: 14991-7. PMID: 8100817
Inhibitor of:
Digoxigenin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
β-Methyl Digoxin, 2.5 mg | sc-219473 | 2.5 mg | $320.00 |