β-Hydroxyisovaleric acid (CAS 625-08-1)
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β-Hydroxyisovaleric acid is a compound utilized in research for its involvement in the catabolism of branched-chain amino acids and as an indicator for metabolic disorders. It is also a key intermediate in the synthesis of β-hydroxy-β-methylbutyrate (HMB), which is researched for its potential effects on muscle metabolism. In organic synthesis, its dual functional groups - a hydroxyl and a carboxylic acid - make it a versatile precursor for the creation of esters and amides, useful in the production of polymers and various bioactive compounds. This multifunctionality places β-hydroxyisovaleric acid at the center of many research endeavors aimed at understanding metabolic processes and advancing the development of new materials and molecules.
β-Hydroxyisovaleric acid (CAS 625-08-1) References
- Biotin deficiency affects both synthesis and degradation of pyruvate carboxylase in rat primary hepatocyte cultures. | Rodríguez-Fuentes, N., et al. 2007. Mol Genet Metab. 92: 222-8. PMID: 17720579
- Increased urinary excretion of beta-hydroxyisovaleric acid in ketotic and non-ketotic type II diabetes mellitus. | Yu, WM., et al. 1990. Clin Chim Acta. 188: 161-8. PMID: 2116243
- Beta-methylcrotonyl-CoA carboxylase deficiency: a new metabolic error in leucine degradation. | Stokke, O., et al. 1972. Pediatrics. 49: 726-35. PMID: 5035417
- Subcellular distribution and partial characterization of an alpha-ketoisocaproate oxidase of rat liver: formation of beta-hydroxyisovaleric acid. | Sabourin, PJ. and Bieber, LL. 1981. Arch Biochem Biophys. 206: 132-44. PMID: 7212712
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
β-Hydroxyisovaleric acid, 5 g | sc-235338 | 5 g | $490.00 |