β-defensin 1 Antibody (M4-14b-H4) is a mouse monoclonal IgG1 kappa light chain antibody that detects human beta-defensin 1 by western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). Anti-beta-defensin 1 antibody (M4-14b-H4) is available as a non-conjugated format. Beta-defensin 1 is a crucial component of the innate immune system, primarily produced in epithelial cells of mucosal surfaces, including the respiratory tract. Beta-defensin 1 plays a significant role in the body′s first line of defense against pathogens, exhibiting broad-spectrum antimicrobial activity against bacteria, viruses, and fungi. Beta-defensin 1′s ability to disrupt microbial membranes is vital for maintaining mucosal integrity and preventing infections, particularly in the lungs where beta-defensin 1 contributes to antimicrobial properties of airway surface fluid. Beta-defensin 1 interacts with various immune cells, enhancing their response to infections and inflammation. Beta-defensin 1′s presence in human plasma at nanomolar concentrations further underscores beta-defensin 1′s importance in systemic immunity. With beta-defensin 1′s multifaceted role in host defense, beta-defensin 1 monoclonal antibody (M4-14b-H4) is an essential tool for researchers studying innate immunity and mechanisms underlying respiratory health.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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β-defensin 1 Antibody (M4-14b-H4) References:
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