Date published: 2026-3-17

1-800-457-3801

SCBT Portrait Logo
Seach Input

β-defensin 1 Antibody (M4-14b-H4): sc-65501

2.0(1)
Write a reviewAsk a question

Datasheets
  • β-defensin 1 Antibody (M4-14b-H4) is a mouse monoclonal IgG1 κ β-defensin 1 antibody provided at 100 µg/ml
  • raised against a synthetic peptide mapping to amino acids 1-36 of β-defensin 1 of human origin
  • recommended for detection of β-defensin 1 of human origin by WB and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for β-defensin 1 Antibody (M4-14b-H4). This work is in progress.
    Crispr Promo Banner

    QUICK LINKS

    SEE ALSO...

    β-defensin 1 Antibody (M4-14b-H4) is a mouse monoclonal IgG1 kappa light chain antibody that detects human beta-defensin 1 by western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). Anti-beta-defensin 1 antibody (M4-14b-H4) is available as a non-conjugated format. Beta-defensin 1 is a crucial component of the innate immune system, primarily produced in epithelial cells of mucosal surfaces, including the respiratory tract. Beta-defensin 1 plays a significant role in the body′s first line of defense against pathogens, exhibiting broad-spectrum antimicrobial activity against bacteria, viruses, and fungi. Beta-defensin 1′s ability to disrupt microbial membranes is vital for maintaining mucosal integrity and preventing infections, particularly in the lungs where beta-defensin 1 contributes to antimicrobial properties of airway surface fluid. Beta-defensin 1 interacts with various immune cells, enhancing their response to infections and inflammation. Beta-defensin 1′s presence in human plasma at nanomolar concentrations further underscores beta-defensin 1′s importance in systemic immunity. With beta-defensin 1′s multifaceted role in host defense, beta-defensin 1 monoclonal antibody (M4-14b-H4) is an essential tool for researchers studying innate immunity and mechanisms underlying respiratory health.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    β-defensin 1 Antibody (M4-14b-H4) References:

    1. Mouse beta-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs.  |  Bals, R., et al. 1999. Infect Immun. 67: 3542-7. PMID: 10377137
    2. Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6.  |  Yang, D., et al. 1999. Science. 286: 525-8. PMID: 10521347
    3. Beta-defensin expression in human mammary gland epithelia.  |  Tunzi, CR., et al. 2000. Pediatr Res. 48: 30-5. PMID: 10879797
    4. Abundant human beta-defensin-1 expression in milk and mammary gland epithelium.  |  Jia, HP., et al. 2001. J Pediatr. 138: 109-12. PMID: 11148522
    5. Expression of beta-defensin 1 and 2 mRNA by human monocytes, macrophages and dendritic cells.  |  Duits, LA., et al. 2002. Immunology. 106: 517-25. PMID: 12153515
    6. Airway β-Defensin-1 Protein Is Elevated in COPD and Severe Asthma.  |  Baines, KJ., et al. 2015. Mediators Inflamm. 2015: 407271. PMID: 26568662
    7. Human beta-defensin 1, a new animal toxin-like blocker of potassium channel.  |  Feng, J., et al. 2016. Toxicon. 113: 1-6. PMID: 26854370
    8. Modulation of Human β-Defensin-1 Production by Viruses.  |  Ryan, LK. and Diamond, G. 2017. Viruses. 9: PMID: 28635669
    9. hBD-1: a novel beta-defensin from human plasma.  |  Bensch, KW., et al. 1995. FEBS Lett. 368: 331-5. PMID: 7628632
    10. Human airway epithelia express a beta-defensin.  |  McCray, PB. and Bentley, L. 1997. Am J Respir Cell Mol Biol. 16: 343-9. PMID: 9070620
    11. The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry.  |  Liu, L., et al. 1997. Genomics. 43: 316-20. PMID: 9268634
    12. Mouse beta defensin-1 is a functional homolog of human beta defensin-1.  |  Morrison, GM., et al. 1998. Mamm Genome. 9: 453-7. PMID: 9585433

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    β-defensin 1 Antibody (M4-14b-H4)

    sc-65501
    100 µg/ml
    $322.00