Molecular structure of β-cyano-L-Alanine, CAS Number: 6232-19-5
β-cyano-L-Alanine (CAS 6232-19-5)
Alternate Names:
BCA
Application:
β-cyano-L-Alanine is a reversible inhibitor of the H2S-synthesizing enzyme cystathionine γ lyase
CAS Number:
6232-19-5
Molecular Weight:
114.1
Molecular Formula:
C4H6N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
β-cyano-L-Alanine (BCA) is a reversible inhibitor of the H2S-synthesizing enzyme CTH (CSE). β-cyano-L-Alanine blocks H2S synthesis activity in rat liver preparations with an IC50 value of 6.5 muM and increases blood pressure in anaesthetized rats induced with hemorrhagic shock by inhibiting endogenous H2S synthesis. β-cyano-L-Alanine at 50 mg/kg blocked both L-cysteine- and LPS-induced hyperalgesia in rats. Hydrogen sulfide (H2S) is a naturally-occurring gasotransmitter with vasodilator and inflammatory modulating activity. H2S is synthesized naturally in a range of mammalian tissues principally by the activity of two enzymes, CTH (cystathionine gamma lyase CSE) and cystathioninebeta synthetase (CBS).
β-cyano-L-Alanine (CAS 6232-19-5) References
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Inhibitor of:
CTH, and IQGAP1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
β-cyano-L-Alanine, 10 mg | sc-205546 | 10 mg | $14.00 | |||
β-cyano-L-Alanine, 50 mg | sc-205546A | 50 mg | $48.00 |