β-Amyrin (CAS 559-70-6)
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β-Amyrin, a member of the naturally occurring pentacyclic triterpenes, possesses notable anti-inflammatory, antimicrobial, antioxidative, and chemoprotective properties. It exerts its effects by activating cannabinoid receptors CB1 and CB2 while also suppressing the production of cytokines and the expression of NF-κB, CREB, and cyclooxygenase 2. research into the mechanisms of action of beta-Amyrin and its derivatives is contributing to a deeper understanding of how such natural compounds interact with biological systems. Beta-Amyrin is recognized for its significant role in the biosynthesis of various plant sterols and saponins, which are vital for plant structure and defense mechanisms against pathogens and herbivores.
β-Amyrin (CAS 559-70-6) References
- Amyrin attenuates scopolamine-induced cognitive impairment in mice. | Park, SJ., et al. 2014. Biol Pharm Bull. 37: 1207-13. PMID: 24989012
- Positive effects of β-amyrin on pentobarbital-induced sleep in mice via GABAergic neurotransmitter system. | Jeon, SJ., et al. 2015. Behav Brain Res. 291: 232-236. PMID: 26026786
- β-Amyrin induces angiogenesis in vascular endothelial cells through the Akt/endothelial nitric oxide synthase signaling pathway. | Ishii, M., et al. 2015. Biochem Biophys Res Commun. 467: 676-82. PMID: 26498523
- Practical Synthesis of α-Amyrin, β-Amyrin, and Lupeol: The Potential Natural Inhibitors of Human Oxidosqualene Cyclase. | Chen, D., et al. 2017. Arch Pharm (Weinheim). 350: PMID: 29027714
- Enhanced β-Amyrin Synthesis in Saccharomyces cerevisiae by Coupling An Optimal Acetyl-CoA Supply Pathway. | Liu, H., et al. 2019. J Agric Food Chem. 67: 3723-3732. PMID: 30808164
- β-Amyrin Ameliorates Alzheimer's Disease-Like Aberrant Synaptic Plasticity in the Mouse Hippocampus. | Park, HJ., et al. 2020. Biomol Ther (Seoul). 28: 74-82. PMID: 31357749
- β-amyrin-induced apoptosis in Candida albicans triggered by calcium. | Kwun, MS., et al. 2021. Fungal Biol. 125: 630-636. PMID: 34281656
- In silico and in vitro evaluation of efflux pumps inhibition of α,β-amyrin. | Oliveira, RC., et al. 2022. J Biomol Struct Dyn. 40: 12785-12799. PMID: 34528866
- α-Amyrin and β-Amyrin Isolated from Celastrus hindsii Leaves and Their Antioxidant, Anti-Xanthine Oxidase, and Anti-Tyrosinase Potentials. | Viet, TD., et al. 2021. Molecules. 26: PMID: 34885832
- β-Amyrin ameliorates diabetic nephropathy in mice and regulates the miR-181b-5p/HMGB2 axis in high glucose-stimulated HK-2 cells. | Xu, W., et al. 2022. Environ Toxicol. 37: 637-649. PMID: 34894065
- Structural analysis of mixed α- and β-amyrin samples. | Gómez-Pulido, LDM., et al. 2022. R Soc Open Sci. 9: 211787. PMID: 35425629
- Enhanced production of amyrin in Yarrowia lipolytica using a combinatorial protein and metabolic engineering approach. | Kong, J., et al. 2022. Microb Cell Fact. 21: 186. PMID: 36085205
- Antibacterial Mode of Action of β-Amyrin Promotes Apoptosis-Like Death in Escherichia coli by Producing Reactive Oxygen Species. | Han, G. and Lee, DG. 2022. J Microbiol Biotechnol. 32: 1547-1552. PMID: 36384774
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
β-Amyrin, 10 mg | sc-252376 | 10 mg | $510.00 |