Date published: 2025-11-12

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β-1,3-Glucan (CAS 9051-97-2)

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Alternate Names:
beta-D-Glucan; 1,3-b-D-Glucan; b-1,3-D-Glucan; Paramylon
CAS Number:
9051-97-2
Molecular Weight:
~500,000 Da
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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β-1,3-Glucan is a naturally occurring polysaccharide that is widely researched for its structural role in the cell walls of fungi, bacteria, and certain plants. In research, it is frequently examined for its ability to activate immune responses, as it is recognized by the immune system′s pattern recognition receptors. It also serves as a model compound to study the physicochemical properties of polysaccharides, including solubility, viscosity, and the ability to form gels or films. β-1,3-Glucan is utilized in the study of fungal biology and ecology, helping scientists understand the structure-function relationship of fungal cell walls and their resistance to environmental stresses. Additionally, this compound is used in agricultural research to enhance the innate resistance of plants to pathogens by priming their defense mechanisms. It also plays a role in the development of biodegradable materials and biofilms due to its biocompatible and structural properties.


β-1,3-Glucan (CAS 9051-97-2) References

  1. Endotoxin and β-(1 → 3)-glucan exposure in poultry and ruminant clinics.  |  Samadi, S., et al. 2011. J Environ Monit. 13: 3254-61. PMID: 22009487
  2. Dectin-1 activation controls maturation of β-1,3-glucan-containing phagosomes.  |  Mansour, MK., et al. 2013. J Biol Chem. 288: 16043-54. PMID: 23609446
  3. β-1,3-glucan modifying enzymes in Aspergillus fumigatus.  |  Mouyna, I., et al. 2013. Front Microbiol. 4: 81. PMID: 23616783
  4. Dectin-1 Controls TLR9 Trafficking to Phagosomes Containing β-1,3 Glucan.  |  Khan, NS., et al. 2016. J Immunol. 196: 2249-61. PMID: 26829985
  5. The recognition mechanism of triple-helical β-1,3-glucan by a β-1,3-glucanase.  |  Qin, Z., et al. 2017. Chem Commun (Camb). 53: 9368-9371. PMID: 28787048
  6. β-(1,3)-Glucan derived from Candida albicans induces inflammatory cytokines from macrophages and lamina propria mononuclear cells derived from patients with Crohn's disease.  |  Mori, K., et al. 2018. Intest Res. 16: 384-392. PMID: 30090037
  7. Effects of beta-1,3-glucan (AletaTM) on vaccination response in broiler chickens.  |  Horst, G., et al. 2019. Poult Sci. 98: 1643-1647. PMID: 30476311
  8. Synthesis of β-1,3-glucan mimics by β-1,3-glucan trisaccharyl monomer polymerization.  |  Miyagawa, A. and Yamamura, H. 2020. Carbohydr Polym. 227: 115105. PMID: 31590847
  9. Supplementation with beta-1,3-glucan improves productivity, immunity and antioxidative status in transition Holstein cows.  |  Xia, WH., et al. 2021. Res Vet Sci. 134: 120-126. PMID: 33360572
  10. Animal Allergens, Endotoxin, and β-(1,3)-Glucan in Small Animal Practices: Exposure Levels at Work and in Homes of Veterinary Staff.  |  Zahradnik, E., et al. 2022. Ann Work Expo Health. 66: 27-40. PMID: 34363388
  11. Evaluating β-1,3-glucan synthesis inhibition using emulsion formation as an indicator.  |  Nerome, S., et al. 2021. J Microbiol Methods. 190: 106327. PMID: 34517039
  12. Yeast β-1,3-glucan production by an outer membrane β-1,6-glucanase: process optimization, structural characterization and immunomodulatory activity.  |  Qiao, Y., et al. 2022. Food Funct. 13: 3917-3930. PMID: 35289343
  13. β-1,3-Glucan/chitin unmasking in the Saccharomyces cerevisiae mutant, Δmnn9, promotes immune response and resistance of the Pacific oyster (Crassostrea gigas) to Vibrio coralliilyticus infection.  |  Loor, A., et al. 2022. Fish Shellfish Immunol. 131: 470-479. PMID: 36115606
  14. β-1,3-Glucan synthesis, novel supramolecular self-assembly, characterization and application.  |  Pylkkänen, R., et al. 2022. Nanoscale. 14: 15533-15541. PMID: 36194159
  15. Nature of β-1,3-Glucan-Exposing Features on Candida albicans Cell Wall and Their Modulation.  |  de Assis, LJ., et al. 2022. mBio. 13: e0260522. PMID: 36218369

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

β-1,3-Glucan, 1 g

sc-213514
1 g
$190.00

β-1,3-Glucan, 5 g

sc-213514A
5 g
$679.00