Date published: 2025-10-2

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Berberine hemisulfate (CAS 633-66-9)

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Application:
Berberine hemisulfate is an alkaloid compound with anti-inflammatory activity that fluoresces under ultraviolet light
CAS Number:
633-66-9
Molecular Weight:
384.4
Molecular Formula:
C20H18NO41/2SO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Berberine hemisulfate is a compound that functions as an inhibitor of certain enzymes involved in cellular processes. It exerts its mechanism of action by binding to specific targets within the cell, thereby interfering with their normal function. This disruption ultimately leads to alterations in cellular signaling pathways and gene expression. Berberine hemisulfate′s mechanism of action involves modulating the activity of key proteins involved in various cellular processes, impacting their function and downstream effects. Berberine Hemisulfate′s role in experimental applications involves its ability to perturb cellular processes and pathways, providing molecular mechanisms underlying various biological phenomena. Its interactions at the molecular and cellular level make it a asset in elucidating the workings of cellular processes and signaling pathways.


Berberine hemisulfate (CAS 633-66-9) References

  1. The anti-inflammatory potential of berberine in vitro and in vivo.  |  Kuo, CL., et al. 2004. Cancer Lett. 203: 127-37. PMID: 14732220
  2. Structural Changes and Associated Reduction of Hydraulic Conductance in Roots of Sorghum bicolor L. following Exposure to Water Deficit.  |  Cruz, RT., et al. 1992. Plant Physiol. 99: 203-12. PMID: 16668850
  3. Enhanced activity of strobilurin and fludioxonil by using berberine and phenolic compounds to target fungal antioxidative stress response.  |  Kim, JH., et al. 2007. Lett Appl Microbiol. 45: 134-41. PMID: 17651208
  4. Efficacy of berberine in patients with type 2 diabetes mellitus.  |  Yin, J., et al. 2008. Metabolism. 57: 712-7. PMID: 18442638
  5. Traditional chinese medicine in treatment of metabolic syndrome.  |  Yin, J., et al. 2008. Endocr Metab Immune Disord Drug Targets. 8: 99-111. PMID: 18537696
  6. On the mechanism of antidepressant-like action of berberine chloride.  |  Kulkarni, SK. and Dhir, A. 2008. Eur J Pharmacol. 589: 163-72. PMID: 18585703
  7. Current investigational drugs for major depression.  |  Kulkarni, SK. and Dhir, A. 2009. Expert Opin Investig Drugs. 18: 767-88. PMID: 19426122
  8. sigma-1 receptors in major depression and anxiety.  |  Kulkarni, SK. and Dhir, A. 2009. Expert Rev Neurother. 9: 1021-34. PMID: 19589051
  9. Berberine and Coptidis rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations.  |  Tang, J., et al. 2009. J Ethnopharmacol. 126: 5-17. PMID: 19686830
  10. A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs.  |  Sun, Y., et al. 2009. Anticancer Drugs. 20: 757-69. PMID: 19704371
  11. Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression.  |  Zhang, H., et al. 2010. Metabolism. 59: 285-92. PMID: 19800084
  12. Berberine: a plant alkaloid with therapeutic potential for central nervous system disorders.  |  Kulkarni, SK. and Dhir, A. 2010. Phytother Res. 24: 317-24. PMID: 19998323
  13. The inhibition of inflammatory molecule expression on 3T3-L1 adipocytes by berberine is not mediated by leptin signaling.  |  Choi, BH., et al. 2009. Nutr Res Pract. 3: 84-8. PMID: 20016706
  14. Berberine inhibits HIV protease inhibitor-induced inflammatory response by modulating ER stress signaling pathways in murine macrophages.  |  Zha, W., et al. 2010. PLoS One. 5: e9069. PMID: 20161729
  15. Berberine inhibits NADPH oxidase mediated superoxide anion production in macrophages.  |  Sarna, LK., et al. 2010. Can J Physiol Pharmacol. 88: 369-78. PMID: 20393601
  16. Nitrogen supply affects ion homeostasis by modifying root Casparian strip formation through the miR528-LAC3 module in maize.  |  Guo, Y., et al. 2023. Plant Commun. 4: 100553. PMID: 36681862

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Berberine hemisulfate, 1 g

sc-202496
1 g
$31.00