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Benzyl selenocyanate (CAS 4671-93-6)

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Alternate Names:
Selenocyanic acid, benzyl ester
Application:
Benzyl selenocyanate is a synthetic chemopreventative agent
CAS Number:
4671-93-6
Molecular Weight:
196.11
Molecular Formula:
C8H7NSe
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Benzyl selenocyanate is a versatile synthetic organoselenium chemopreventive agent. Benzyl selenocyanate has been found to be effective in several animal tumor model systems.


Benzyl selenocyanate (CAS 4671-93-6) References

  1. Cancer chemoprevention by garlic and garlic-containing sulfur and selenium compounds.  |  El-Bayoumy, K., et al. 2006. J Nutr. 136: 864S-869S. PMID: 16484582
  2. Metabolism of [14C]benzyl selenocyanate in the F344 rat.  |  el-Bayoumy, K., et al. 1991. Chem Res Toxicol. 4: 560-5. PMID: 1793806
  3. Inhibition of nuclear factor-kappaB DNA binding by organoselenocyanates through covalent modification of the p50 subunit.  |  Chen, KM., et al. 2007. Cancer Res. 67: 10475-83. PMID: 17974991
  4. Spectral modification and catalytic inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2A6, and 2A13 by four chemopreventive organoselenium compounds.  |  Shimada, T., et al. 2011. Chem Res Toxicol. 24: 1327-37. PMID: 21732699
  5. Potent anti-proliferative activities of organochalcogenocyanates towards breast cancer.  |  Banerjee, K., et al. 2018. Org Biomol Chem. 16: 8769-8782. PMID: 30403243
  6. Comparative effect of inorganic and organic selenocyanate derivatives in mammary cancer chemoprevention.  |  Ip, C., et al. 1994. Carcinogenesis. 15: 187-92. PMID: 8313507
  7. Contrasting patterns of selenium excretion by female CD rats treated with chemically related chemopreventive organic selenocyanate compounds.  |  Sohni, OS., et al. 1995. Anticancer Res. 15: 1849-56. PMID: 8572569
  8. Inhibition of 2-nitropropane-induced rat liver DNA and RNA damage by benzyl selenocyanate.  |  Fiala, ES., et al. 1997. Carcinogenesis. 18: 1809-15. PMID: 9328179
  9. Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation.  |  Fiala, ES., et al. 1998. Carcinogenesis. 19: 597-604. PMID: 9600343
  10. Evaluation of benzyl selenocyanate glutathione conjugate for potential chemopreventive properties in colon carcinogenesis.  |  Kawamori, T., et al. 1998. Int J Oncol. 13: 29-34. PMID: 9625800

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Benzyl selenocyanate, 50 mg

sc-204642
50 mg
$139.00

Benzyl selenocyanate, 100 mg

sc-204642A
100 mg
$247.00