Benzyl N-Acetyl-6-O-benzyl-α-D-muramic Acid Methyl Ester (CAS 107671-54-5)

Benzyl N-Acetyl-6-O-benzyl-α-D-muramic Acid Methyl Ester is a synthetic derivative of muramic acid, which is an essential component of bacterial cell wall peptidoglycan. This compound is primarily used in the field of biochemical research to study the structure and function of bacterial cell walls, particularly focusing on the biosynthesis and assembly of peptidoglycan layers. The inclusion of benzyl and methyl ester groups provides stability to the molecule, allowing for detailed studies of the enzymatic processes involved in cell wall construction and modification. This chemical serves as a specific substrate or inhibitor in enzymatic assays targeting enzymes such as transglycosylases and transpeptidases, which are vital for the cross-linking of peptidoglycan strands and overall cell wall integrity. By studying the interaction of this compound with such enzymes, researchers can gain insights into the mechanisms of bacterial growth and division, as well as resistance to antibiotics that target cell wall synthesis. Additionally, Benzyl N-Acetyl-6-O-benzyl-α-D-muramic Acid Methyl Ester is utilized in the development of novel antibacterial strategies, providing a model to understand how modifications in the chemical structure of muramic acid derivatives can affect their biological activity. These studies contribute significantly to the field of microbiology and antibiotic research, helping to explain key processes in bacterial metabolism and pathogenesis.