Benzyl Chloroformate (CAS 501-53-1)
Available in US only.
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Benzyl Chloroformate (30-35% in Toluene) is widely used in organic synthesis, particularly for the introduction of the benzyloxycarbonyl (Cbz) protecting group in amino acid and peptide chemistry. This solution facilitates the protection of amine groups during peptide bond formation, which is for the synthesis of complex peptide structures. In research, Benzyl Chloroformate is explored for its efficiency and selectivity in these reactions, aiding in the development of methodologies that improve peptide synthesis techniques. Benzyl Chloroformate (30-35% in Toluene) is utilized in the study of kinetic and mechanistic aspects of esterification and carbonylation reactions. By using Benzyl Chloroformate in various organic synthesis contexts, researchers can better understand reaction pathways and develop more efficient synthetic routes for organic compounds.
Benzyl Chloroformate (CAS 501-53-1) References
- A sensitive quantification approach for detection of HETE-CP adduct after benzyl chloroformate derivatization using ultra-high-pressure liquid chromatography tandem mass spectrometry. | Chen, B., et al. 2019. Anal Bioanal Chem. 411: 3405-3415. PMID: 31011788
- A sensitive method for the quantification of short-chain fatty acids by benzyl chloroformate derivatization combined with GC-MS. | Li, M., et al. 2020. Analyst. 145: 2692-2700. PMID: 32073098
- A step-economic and one-pot access to chiral Cα-tetrasubstituted α-amino acid derivatives via a bicyclic imidazole-catalyzed direct enantioselective C-acylation. | Wang, M., et al. 2020. Chem Sci. 11: 4801-4807. PMID: 34122937
- Enantioselective Catalytic Dearomative Addition of Grignard Reagents to 4-Methoxypyridinium Ions. | Guo, Y., et al. 2021. ACS Catal. 11: 8476-8483. PMID: 34306813
- Development of Triiodothyronine Polymeric Nanoparticles for Targeted Delivery in the Cardioprotection against Ischemic Insult. | Karakus, OO., et al. 2021. Biomedicines. 9: PMID: 34829942
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- Targeted Synthesis of 3,3'-, 3,4'- and 3,6'-Phenylpropanoid Sucrose Esters. | Kathy, WPW., et al. 2022. Molecules. 27: PMID: 35056850
- Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S-Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. | Zhang, J., et al. 2022. J Am Chem Soc. 144: 9910-9919. PMID: 35622017
- Chemoenzymatic Synthesis of Select Intermediates and Natural Products of the Desferrioxamine E Siderophore Pathway. | Hoffmann, KM., et al. 2022. Molecules. 27: PMID: 36234688
- Four-Component Strain-Release-Driven Synthesis of Functionalized Azetidines. | Tyler, JL., et al. 2022. Angew Chem Int Ed Engl. 61: e202214049. PMID: 36300572
- Synthesis of Saturated N-Heterocycles via a Catalytic Hydrogenation Cascade. | Wagener, T., et al. 2022. Adv Synth Catal. 364: 3366-3371. PMID: 36589139
- A method for the synthesis of unsymmetric bisphosphoric analogs of α-amino acids. | Kuźnik, A., et al. 2023. RSC Adv. 13: 18908-18915. PMID: 37362601
- C-Methylated Spermidine Derivatives: Convenient Syntheses and Antizyme-Related Effects. | Khomutov, MA., et al. 2023. Biomolecules. 13: PMID: 37371496
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Benzyl Chloroformate, 25 ml | sc-291952 | 25 ml | $50.00 | |||
| US: Only available in the US | ||||||
Benzyl Chloroformate, 500 ml | sc-291952A | 500 ml | $214.00 | |||
| US: Only available in the US | ||||||