Benzyl 5-Amino-5-deoxy-2,3-O-isopropyl-α-D-mannofuranoside (CAS 91364-19-1)

Benzyl 5-Amino-5-deoxy-2,3-O-isopropyl-α-D-mannofuranoside is a specialized chemical used primarily in the field of carbohydrate chemistry for the synthesis of glycoconjugates and complex carbohydrate structures. This compound features an amino group at the 5-position, which introduces unique functionality into the carbohydrate molecule, making it particularly valuable for bioconjugation and modification studies. The amino group allows for straightforward derivatization through various chemical reactions, including acylation, alkylation, and the formation of amide bonds, facilitating the attachment of diverse probes, labels, or biological molecules. Researchers have utilized this compound in the design and synthesis of targeted drug delivery systems, where the presence of the amino group enables the conjugation of drug molecules directly to the carbohydrate structure, potentially enhancing drug specificity and efficacy. Additionally, this derivative′s modified sugar backbone is useful in studying carbohydrate-protein interactions, especially in the context of cell-surface interactions and receptor binding studies, which are critical in understanding many biological processes and disease mechanisms. Furthermore, the protected groups (benzyl and isopropyl) provide stability and resistance to premature degradation or reaction, making it easier to handle in various experimental conditions.