Date published: 2026-2-2

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Benzophenone-4-isothiocyanate (CAS 26328-59-6)

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Alternate Names:
(4-isothiocyanatophenyl)-phenylmethanone
Application:
Benzophenone-4-isothiocyanate is a benzophenone-based, hydroxyl- and photoreactive crosslinker
CAS Number:
26328-59-6
Purity:
≥90%
Molecular Weight:
239.29
Molecular Formula:
C14H9NOS
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Benzophenone-4-isothiocyanate is a photoreactive benzophenone-based reagent shown to be useful for synthesizing photoreactive oligonucleotides and peptides.


Benzophenone-4-isothiocyanate (CAS 26328-59-6) References

  1. Synthesis and characterization of fluorescent and photoactivatable MIP-1alpha ligands and interactions with chemokine receptors CCR1 and CCR5.  |  Zoffmann, S., et al. 2001. J Med Chem. 44: 215-22. PMID: 11170631
  2. Direct activation of cyclin-dependent kinase 2 by human papillomavirus E7.  |  He, W., et al. 2003. J Virol. 77: 10566-74. PMID: 12970441
  3. Interaction of plasma gelsolin with tropomyosin.  |  Koepf, EK. and Burtnick, LD. 1992. FEBS Lett. 309: 56-8. PMID: 1324850
  4. Determination of accessible amino groups on surfaces by chemical derivatization with 3,5-bis(trifluoromethyl)phenyl isothiocyanate and XPS/NEXAFS analysis.  |  Graf, N., et al. 2010. Anal Bioanal Chem. 396: 725-38. PMID: 19890629
  5. Benzophenone-based photochemical micropatterning of biomolecules to create model substrates and instructive biomaterials.  |  Turgeon, AJ., et al. 2014. Methods Cell Biol. 121: 231-42. PMID: 24560513
  6. The combined effects of matrix stiffness and growth factor immobilization on the bioactivity and differentiation capabilities of adipose-derived stem cells.  |  Banks, JM., et al. 2014. Biomaterials. 35: 8951-9. PMID: 25085859
  7. Patterned Co-culture of Live Cells on a Microchip by Photocrosslinking with Benzophenone.  |  Sato, K., et al. 2016. Anal Sci. 32: 113-6. PMID: 26753716
  8. Characterization of polypeptides immunoprecipitable from Pichinde virus-infected BHK-21 cells.  |  Harnish, DG., et al. 1981. J Virol. 38: 840-8. PMID: 6264158
  9. Photochemical linkage of antibodies to silicon chips.  |  Sundarababu, G., et al. 1995. Photochem Photobiol. 61: 540-4. PMID: 7568400
  10. Benzophenone photophores in biochemistry.  |  Dormán, G. and Prestwich, GD. 1994. Biochemistry. 33: 5661-73. PMID: 8180191

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Benzophenone-4-isothiocyanate, 100 mg

sc-214587
100 mg
$196.00