Date published: 2026-4-5

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Benzo(D) Isothiazol-3-one (CAS 2634-33-5)

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Alternate Names:
1,2-Benzisothiazol-3(2H)-one; 3-Hydroxy-1,2-benzisothiazole; Acticide BIT
CAS Number:
2634-33-5
Molecular Weight:
151.19
Molecular Formula:
C7H5NOS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Benzo(D) Isothiazol-3-one functions as a potent biocide, exerting its mechanism of action by disrupting the cellular membranes of microorganisms. This disruption leads to the leakage of cellular contents and ultimately results in cell death. Benzo(D) Isothiazol-3-one′s mechanism of action involves its ability to interact with the lipid bilayer of the cell membrane, causing destabilization and permeabilization. This leads to the loss of membrane integrity and the subsequent collapse of cellular processes. Benzo(D) isothiazol-3-one′s mechanism of action at the molecular level involves its interaction with specific components of the cell membrane, leading to the disruption of membrane function and integrity. This disruption ultimately impairs the microorganism′s ability to maintain homeostasis and carry out vital cellular functions, resulting in its demise.


Benzo(D) Isothiazol-3-one (CAS 2634-33-5) References

  1. In silico identification of potential inhibitors targeting Streptococcus mutans sortase A.  |  Luo, H., et al. 2017. Int J Oral Sci. 9: 53-62. PMID: 28358034
  2. Identification of novel small-molecular inhibitors of Staphylococcus aureus sortase A using hybrid virtual screening.  |  Volynets, GP., et al. 2022. J Antibiot (Tokyo). 75: 321-332. PMID: 35440771

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Benzo(D) Isothiazol-3-one, 1 g

sc-207325
1 g
$337.00

Benzo(D) Isothiazol-3-one, 5 g

sc-207325A
5 g
$439.00