Date published: 2026-4-25

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Benzo-18-crown-6 (CAS 14098-24-9)

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CAS Number:
14098-24-9
Molecular Weight:
312.36
Molecular Formula:
C16H24O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Benzo-18-crown-6, a macrocyclic polyether compound comprising 18 carbon atoms forming a cyclic ring, exhibits solubility in various organic solvents. This compound has been the subject of research and finds application in a range of scientific fields. It serves as a catalyst in organic synthesis reactions, facilitating the production of polyethers, and acts as a ligand to enhance the water solubility of organic compounds. Additionally, benzo-18-crown-6 plays a role in molecular recognition studies, enabling the detection and identification of specific molecules through its molecular recognition capabilities.


Benzo-18-crown-6 (CAS 14098-24-9) References

  1. Hydration to benzo-15-crown-5, benzo-18-crown-6 and the benzo-18-crown-6-potassium ion complex in the low-polar organic solvents.  |  Kikuchi, Y., et al. 2001. Anal Sci. 17: 421-4. PMID: 11990620
  2. Crown ether appended cyclam receptors for cationic guests.  |  Bernhardt, PV. and Hayes, EJ. 2002. Inorg Chem. 41: 2892-902. PMID: 12033897
  3. Stable supramolecular dimer of self-complementary benzo-18-crown-6 with a pendant protonated amino arm.  |  Kryatova, OP., et al. 2002. Chem Commun (Camb). 3014-5. PMID: 12536793
  4. Crystal and molecular structures of ionophore-siderophore host-guest supramolecular assemblies relevant to molecular recognition.  |  Dhungana, S., et al. 2003. J Am Chem Soc. 125: 14760-7. PMID: 14640651
  5. Electrochemical investigation of Pb2+ binding and transport through a polymerized crystalline colloidal array hydrogel containing benzo-18-crown-6.  |  Geary, CD., et al. 2005. Anal Chem. 77: 185-92. PMID: 15623295
  6. 2,4-dithiouracil: the reproducible H-bonded structural motifs in the complexes with 18-membered crown ethers.  |  Wang, WJ., et al. 2005. Org Biomol Chem. 3: 3054-8. PMID: 16186939
  7. Laser spectroscopic study on the conformations and the hydrated structures of benzo-18-crown-6-ether and dibenzo-18-crown-6-ether in supersonic jets.  |  Kusaka, R., et al. 2007. Phys Chem Chem Phys. 9: 4452-9. PMID: 17690770
  8. Equilibrium studies on complexation in water and solvent extraction of zinc(II) and cadmium(II) with benzo-18-crown-6.  |  Katsuta, S., et al. 2000. Talanta. 51: 637-44. PMID: 18967896
  9. Extraction of sodium and potassium perchlorates with benzo-18-crown-6 into various organic solvents. Quantitative elucidation of anion effects on the extraction-ability and -selectivity for Na(+) and K(+).  |  Takeda, Y., et al. 2002. Talanta. 56: 505-13. PMID: 18968523
  10. A white phosphorescent coordination polymer with Cu2I2 alternating units linked by benzo-18-crown-6.  |  Wu, F., et al. 2014. Dalton Trans. 43: 12463-6. PMID: 24886808
  11. Solvent Effects on the Encapsulation of Divalent Ions by Benzo-18-Crown-6 and Benzo-15-Crown-5.  |  Inokuchi, Y., et al. 2015. J Phys Chem A. 119: 8097-105. PMID: 26135940
  12. Geometric and Electronic Structures of Ag+(benzo-18-crown-6), Ag+(dibenzo-18-crown-6), and Ag+(dibenzo-15-crown-5) Complexes Investigated by Cold Gas-Phase Spectroscopy.  |  Kitamura, Y., et al. 2019. J Phys Chem A. 123: 9185-9192. PMID: 31545041
  13. Chromatographic Purification of Lithium, Vanadium, and Uranium from Seawater Using Organic Composite Adsorbents Composed of Benzo-18-Crown-6 and Benzo-15-Crown-5 Embedded in Highly Porous Silica Beads.  |  Tachibana, Y., et al. 2022. ACS Omega. 7: 27410-27421. PMID: 35967073
  14. Solvent-polarity reconfigurable fluorescent 4-piperazino-N-aryl-1,8-naphthalimide crown ether logic gates.  |  Gauci, G. and Magri, DC. 2022. RSC Adv. 12: 35270-35278. PMID: 36540226

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Benzo-18-crown-6, 1 g

sc-239302
1 g
$44.00