Molecular structure of Benzethonium chloride, CAS Number: 121-54-0
Benzethonium chloride (CAS 121-54-0)
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Alternate Names:
Phemerol chloride; Hyamine 1622; Phemerol chloride
Application:
Benzethonium chloride is a cationic quaternary ammonium surfactant
CAS Number:
121-54-0
Purity:
≥97%
Molecular Weight:
448.08
Molecular Formula:
C27H42NO2•Cl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Benzethonium chloride is a white, crystalline powder highly soluble in water, but insoluble in organic solvents. This compound is recognized for its antiseptic properties, thus is frequently used as a preservative and disinfectant. In the realm of scientific experiments, benzethonium chloride finds diverse applications such as a detergent, antiseptic, disinfectant, and preservative. It is used for preparing laboratory apparatus, serving as a sterilizing agent. Benzethonium chloride is a cationic quaternary ammonium surfactant and anti-infective agent.
Benzethonium chloride (CAS 121-54-0) References
- Benzethonium chloride: a novel anticancer agent identified by using a cell-based small-molecule screen. | Yip, KW., et al. 2006. Clin Cancer Res. 12: 5557-69. PMID: 17000693
- [Formulation of benzethonium chloride into gels]. | Cižmárik, J., et al. 2014. Ceska Slov Farm. 63: 123-6. PMID: 25115665
- Benzethonium chloride activates ER stress and reduces proliferation in HNSCC. | Rayess, HM., et al. 2018. Oral Oncol. 76: 27-33. PMID: 29290283
- Benzalkonium chloride, benzethonium chloride, and chloroxylenol - Three replacement antimicrobials are more toxic than triclosan and triclocarban in two model organisms. | Sreevidya, VS., et al. 2018. Environ Pollut. 235: 814-824. PMID: 29348075
- Effects of Consumer Antimicrobials Benzalkonium Chloride, Benzethonium Chloride, and Chloroxylenol on Colonic Inflammation and Colitis-Associated Colon Tumorigenesis in Mice. | Sanidad, KZ., et al. 2018. Toxicol Sci. 163: 490-499. PMID: 29514330
- Clinical pearl: benzethonium chloride for habit-tic nail deformity. | Geizhals, S. and Lipner, SR. 2019. Cutis. 104: 81-82. PMID: 31487340
- Benzethonium chloride suppresses lung cancer tumorigenesis through inducing p38-mediated cyclin D1 degradation. | Huang, XH., et al. 2019. Am J Cancer Res. 9: 2397-2412. PMID: 31815042
- Proarrhythmic effects induced by benzethonium chloride and domiphen bromide in vitro and in vivo. | Long, Y., et al. 2021. Toxicol Appl Pharmacol. 431: 115731. PMID: 34592322
- Feeding low-level benzethonium chloride can promote the start-up, fast recovery and long-term stable maintenance of partial nitrification for low-ammonium wastewater. | Wu, Z., et al. 2022. Bioresour Technol. 353: 127152. PMID: 35421565
- Impact of benzalkonium chloride, benzethonium chloride and chloroxylenol on bacterial antimicrobial resistance. | Maillard, JY. 2022. J Appl Microbiol. 133: 3322-3346. PMID: 35882500
- Ecological Risk Analysis for Benzalkonium Chloride, Benzethonium Chloride, and Chloroxylenol in US Disinfecting and Sanitizing Products. | Fuchsman, P., et al. 2022. Environ Toxicol Chem. 41: 3095-3115. PMID: 36349534
- Benzethonium chloride as a tungsten corrosion inhibitor in neutral and alkaline media for the post-chemical mechanical planarization application. | Punathil Meethal, R., et al. 2023. J Colloid Interface Sci. 643: 465-479. PMID: 37088050
- Inhibition of acetylcholine esterase and choline esterase by benzethonium chloride and avoidance of the benzethonium chloride carry-over inhibitory effect. | Zaman, Z., et al. 1997. Eur J Clin Chem Clin Biochem. 35: 603-7. PMID: 9298350
Inhibitor of:
β-defensin 108B, β-defensin 111, β-defensin 112, β-defensin 114, EG665927, ficolin A, Gastrokine 2, Grpa, H2-Bl, H2-M3, LACTB2, MANSC4, PQLC3, S100A7A, SerpinA1d, TMEM150B, and Vmn2r123.Activator of:
β-defensin 108C, β-defensin 111, β-defensin 113, β-defensin 3B, β-defensin 41, LYZL1, and Mucin 21.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Benzethonium chloride, 100 g | sc-239299 | 100 g | $53.00 | |||
Benzethonium chloride, 250 g | sc-239299A | 250 g | $105.00 |