Date published: 2025-12-7

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Benzenesulfonyl cyanide (CAS 24224-99-5)

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CAS Number:
24224-99-5
Molecular Weight:
167.19
Molecular Formula:
C7H5NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Benzenesulfonyl cyanide is a chemical compound that functions as a versatile building block in organic synthesis. It acts as a source of the sulfonyl group, enabling the introduction of this functional group into various organic molecules. Through its reaction with nucleophiles, benzenesulfonyl cyanide facilitates the formation of carbon-carbon and carbon-heteroatom bonds, allowing for the synthesis of complex organic compounds. Benzenesulfonyl cyanide involves the activation of the sulfonyl group, which undergoes nucleophilic substitution reactions to form new chemical bonds. This enables the modification of organic molecules and the creation of diverse chemical structures for use in development. Benzenesulfonyl cyanide′s role in organic synthesis involves its ability to serve as a precursor for the introduction of the sulfonyl group, contributing to the development of novel compounds with potential applications in various fields of chemistry.


Benzenesulfonyl cyanide (CAS 24224-99-5) References

  1. Cu2(OTf)2-catalyzed and microwave-controlled preparation of tetrazoles from nitriles and organic azides under mild, safe conditions.  |  Bosch, L. and Vilarrasa, J. 2007. Angew Chem Int Ed Engl. 46: 3926-30. PMID: 17427165
  2. An unexpected reaction of arenesulfonyl cyanides with allylic alcohols: preparation of trisubstituted allyl sulfones.  |  Reddy, LR., et al. 2009. Angew Chem Int Ed Engl. 48: 172-4. PMID: 19040260
  3. Novel C-H functionalization of arenes: palladium-catalyzed synthesis of diaryl sulfides.  |  Anbarasan, P., et al. 2011. Chem Commun (Camb). 47: 3233-5. PMID: 21267485
  4. Synthesis, optical properties and explosive sensing performances of a series of novel π-conjugated aromatic end-capped oligothiophenes.  |  Liu, T., et al. 2013. J Hazard Mater. 246-247: 52-60. PMID: 23280053
  5. C 2-Symmetric chiral bis(oxazoline)-metal complexes in catalytic asymmetric synthesis.  |  Ghosh, AK., et al. 1998. Tetrahedron Asymmetry. 9: 1-45. PMID: 30457575
  6. Synthesis of Highly Substituted Pyridines via [4 + 2] Cycloadditions of Vinylallenes and Sulfonyl Cyanides.  |  Bartko, SG., et al. 2020. J Org Chem. 85: 548-563. PMID: 31797669

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Benzenesulfonyl cyanide, 500 mg

sc-233938
500 mg
$153.00