Date published: 2025-10-18

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Benzenesulfonanilide (CAS 1678-25-7)

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CAS Number:
1678-25-7
Molecular Weight:
233.29
Molecular Formula:
C12H11NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Benzenesulfonanilide, an organic compound classified as an aniline derivative, belongs to the category of aromatic compounds, characterized by the presence of a benzene ring. Specifically, it consists of a benzene ring adorned with a sulfonamide substituent. In scientific applications, benzenesulfonanilide serves a diverse range of purposes. It acts as a reagent in organic synthesis, contributing to the construction of complex molecules. Furthermore, it functions as a catalyst in various organic reactions, facilitating the conversion of reactants into desired products. Additionally, benzenesulfonanilide operates as a ligand in coordination chemistry, forming coordination complexes with metal ions. In organic reactions, benzenesulfonanilide plays a role as a proton donor, enabling the transfer of protons between molecules. Simultaneously, it acts as a Lewis acid, capable of accepting electrons from other molecules. Consequently, it forms robust bonds with other compounds, thereby serving as a catalyst for diverse reactions.


Benzenesulfonanilide (CAS 1678-25-7) References

  1. Analgesic agents without gastric damage: design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-selective inhibitors.  |  Zheng, X., et al. 2007. Bioorg Med Chem. 15: 1014-21. PMID: 17079150
  2. Urearetics: a small molecule screen yields nanomolar potency inhibitors of urea transporter UT-B.  |  Levin, MH., et al. 2007. FASEB J. 21: 551-63. PMID: 17202246
  3. Effect of the oral absorption of benzenesulfonanilide-type cyclooxygenase-1 inhibitors on analgesic action and gastric ulcer formation.  |  Zheng, X., et al. 2008. J Pharm Sci. 97: 5446-52. PMID: 18452178
  4. Analytical strategy based on the use of liquid chromatography and gas chromatography with triple-quadrupole and time-of-flight MS analyzers for investigating organic contaminants in wastewater.  |  Pitarch, E., et al. 2010. Anal Bioanal Chem. 397: 2763-76. PMID: 20428853
  5. Discovery and optimization of benzenesulfonanilide derivatives as a novel class of 11β-HSD1 inhibitors.  |  Rew, Y., et al. 2012. Bioorg Med Chem Lett. 22: 3786-90. PMID: 22542009

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Benzenesulfonanilide, 25 g

sc-487439
25 g
$128.00