Benzamil hydrochloride (CAS 161804-20-2)
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Benzamil hydrochloride is a compound of notable interest in various fields of chemistry, especially in studies concerning ion transport and membrane channel behavior. As a benzyl derivative of amiloride, it is primarily used in research as a selective and potent inhibitor of epithelial sodium channels (ENaC), which are essential for sodium balance in organisms. Biophysical studies utilize benzamil hydrochloride to investigate the kinetics and dynamics of sodium transport across cell membranes, providing insights into the fundamental processes that drive fluid and electrolyte homeostasis. Additionally, it is employed in the development of sensor technologies aimed at detecting sodium levels with high specificity, which is in environmental monitoring and industrial processes.
Benzamil hydrochloride (CAS 161804-20-2) References
- Structure-activity relations of amiloride and its analogues in blocking the mechanosensitive channel in Xenopus oocytes. | Lane, JW., et al. 1992. Br J Pharmacol. 106: 283-6. PMID: 1382778
- Benzamil prevents brain water accumulation in hyponatraemic rats. | Sulyok, E., et al. 2009. Acta Neurochir (Wien). 151: 1121-5. PMID: 19415169
- Modulation of cardiac performance by amiloride and several selected derivatives of amiloride. | Pierce, GN., et al. 1993. J Pharmacol Exp Ther. 265: 1280-91. PMID: 8510009
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Benzamil hydrochloride, 10 mg | sc-252410 | 10 mg | $114.00 |