Benzamidine Hydrochloride CAS: 206752-36-5
MF: C7H8N2•HCl
MW: 156.61
A reversible inhibitor of serine proteases.

Benzamidine Hydrochloride (CAS 206752-36-5)

Benzamidine Hydrochloride | CAS 206752-36-5 is rated 5.0 out of 5 by 1.
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Synonym: Amidinobenzene hydrochloride
Application: A reversible inhibitor of serine proteases
CAS Number: 206752-36-5
Purity: ≥99%
Molecular Weight: 156.61
Molecular Formula: C7H8N2•HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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Benzamidine HCl is a reversible inhibitor of serine proteases, trypsin and trypsin-like enzymes. It has also been shown to be a strong inhibitor of plasminogen (plasmin) and thrombin.


References

Jeffcoate, S.L. and White, N., J. Clin. Endocrinol. Metab. 38, 155, (1974) Deutscher, M.P Meth. Enzymol. 182, 83, (1990) Jazwinski, S.M Meth. Enzymol. 182, 154, (1990) Gegenheimer, P Meth. Enzymol. 182, 174, (1990)

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (100 mg/ml-yellowish, slightly turbid solution; heating may be necessary), and alcohol.
Storage :
Desiccate at 4° C
Melting Point :
86-88° C (lit.)
Boiling Point :
208.5° C at 760 mmHg
Refractive Index :
n20D ~1.57 (Predicted)
IC50 :
Factor XI: IC50 = 120 µM (human)
Ki Data :
Trypsin I: Ki= 31 nM (bovine); Factor X: Ki= 200 nM (human); Prothrombin: Ki= 300 nM (human); Coagulation factor X: Ki= 160 µM (bovine); uPA: Ki= 180 µM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
CV6260000
PubChem CID :
80289
MDL Number :
MFCD00066285
EC Number :
216-795-4
Beilstein Registry :
3594959
SMILES :
C1=CC=C(C=C1)C(=N)N.Cl

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Min W; et al Min W; et al. (PubMed ID: 23524020) utilized Benzamidine Hydrochloride as a positive control when testing compounds for trypsin inhibition.
Date published: 2015-02-12
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