Date published: 2025-9-18

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Benazepril hydrochloride (CAS 86541-74-4)

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Application:
Benazepril hydrochloride is an angiotensin-converting enzyme (ACE) inhibitor
CAS Number:
86541-74-4
Purity:
≥99%
Molecular Weight:
460.96
Molecular Formula:
C24H28N2O5•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Benazepril hydrochloride is an angiotensin-converting enzyme (ACE) inhibitor. Reduces myocardial hypertrophy and blood pressure in spontaneous hypertensive rats.


Benazepril hydrochloride (CAS 86541-74-4) References

  1. Simultaneous determination of benazepril hydrochloride and hydrochlorothiazide by micro-bore liquid chromatography.  |  Panderi, IE. and Parissi-Poulou, M. 1999. J Pharm Biomed Anal. 21: 1017-24. PMID: 10703970
  2. Simultaneous determination of benazepril hydrochloride and benazeprilat in plasma by high-performance liquid chromatography/electrospray-mass spectrometry.  |  Xiao, W., et al. 2005. J Chromatogr B Analyt Technol Biomed Life Sci. 814: 303-8. PMID: 15639452
  3. Hemodynamic effects of benazepril, an angiotensin-converting enzyme inhibitor, as studied in conscious normotensive dogs.  |  Ishibashi, T., et al. 1991. Cardiovasc Drugs Ther. 5: 635-41. PMID: 1652276
  4. General pharmacology of the novel angiotensin converting enzyme inhibitor benazepril hydrochloride. Effects on cardiovascular, visceral and renal functions and on hemodynamics.  |  Yamamoto, S., et al. 1991. Arzneimittelforschung. 41: 913-23. PMID: 1796919
  5. Effects of benazepril hydrochloride in cats with experimentally induced or spontaneously occurring chronic renal failure.  |  Watanabe, T. and Mishina, M. 2007. J Vet Med Sci. 69: 1015-23. PMID: 17984588
  6. Effect of benazepril hydrochloride on cardiac hypertrophy in spontaneously hypertensive rats.  |  Takemori, E., et al. 1991. Arzneimittelforschung. 41: 612-5. PMID: 1834066
  7. The pharmacokinetics of benazepril relative to other ACE inhibitors.  |  Gengo, FM. and Brady, E. 1991. Clin Cardiol. 14: IV44-50; discussion IV51-5. PMID: 1893642
  8. [Preparation and characterization of Forms A and B of benazepril hydrochloride].  |  Fang, H., et al. 2012. Zhejiang Da Xue Xue Bao Yi Xue Ban. 41: 639-46. PMID: 23239655
  9. Benazepril inhibited the NF-κB and TGF-β networking on LV hypertrophy in rats.  |  Yan, SH., et al. 2013. Immunol Lett. 152: 126-34. PMID: 23707880
  10. Development of a new benazepril hydrochloride chewable tablet and evaluation of its bioequivalence for treatment of heart failure in dogs.  |  Qian, M., et al. 2016. J Vet Pharmacol Ther. 39: 98-101. PMID: 26228576
  11. Attenuation of the pressor response to exogenous angiotensin by angiotensin receptor blockers and benazepril hydrochloride in clinically normal cats.  |  Jenkins, TL., et al. 2015. Am J Vet Res. 76: 807-13. PMID: 26309109
  12. IMPACT OF STRESS FACTORS ON OPTICAL ISOMERISM OF BENAZEPRIL HYDROCHLORIDE.  |  Kublin, E., et al. 2015. Acta Pol Pharm. 72: 219-25. PMID: 26642671
  13. Benazepril hydrochloride improves diabetic nephropathy and decreases proteinuria by decreasing ANGPTL-4 expression.  |  Xue, L., et al. 2017. BMC Nephrol. 18: 307. PMID: 28978304
  14. Benazepril hydrochloride protects against doxorubicin cardiotoxicity by regulating the PI3K/Akt pathway.  |  Zhan, L., et al. 2021. Exp Ther Med. 22: 1082. PMID: 34447475

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Benazepril hydrochloride, 50 mg

sc-203526
50 mg
$115.00