Date published: 2025-12-3

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Benazepril-d5 (CAS 1279200-03-1)

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Alternate Names:
(3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid; Lotensin
Application:
Benazepril-d5 is a deuterium labeled ACE inhibitor
CAS Number:
1279200-03-1
Molecular Weight:
429.52
Molecular Formula:
C24H23D5N2O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Labeled Benazepril, which is used as an antihypertensive.


Benazepril-d5 (CAS 1279200-03-1) References

  1. Effects of once-daily benazepril therapy on exercise tolerance and manifestations of chronic congestive heart failure. The Benazepril Heart Failure Study Group.  |  Colfer, HT., et al. 1992. Am J Cardiol. 70: 354-8. PMID: 1632402
  2. Impact of Lotensin and Salviae on the changes of TGF-beta1 and its receptors in a rat model of chronic cyclosporine-induced nephropathy.  |  Peng, B., et al. 2006. Transplant Proc. 38: 2183-6. PMID: 16980037
  3. Benazepril. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in hypertension and congestive heart failure.  |  Balfour, JA. and Goa, KL. 1991. Drugs. 42: 511-39. PMID: 1720384
  4. The pharmacokinetics of benazepril relative to other ACE inhibitors.  |  Gengo, FM. and Brady, E. 1991. Clin Cardiol. 14: IV44-50; discussion IV51-5. PMID: 1893642
  5. Antihypertensive and organ-protective effects of benazepril.  |  Barrios, V. and Escobar, C. 2010. Expert Rev Cardiovasc Ther. 8: 1653-71. PMID: 21108548
  6. Benazepril in dogs with asymptomatic mitral valve disease.  |  Brennan, M. and Stavisky, J. 2015. Vet Rec. 177: 392. PMID: 26475899
  7. IGF-1R Inhibitor Ameliorates Diabetic Nephropathy with Suppressed HMGN1/TLR4 Pathway.  |  Yu, J., et al. 2018. Endocr Metab Immune Disord Drug Targets. 18: 241-250. PMID: 29384065
  8. Haemodynamic and pharmacological effects of the converting enzyme inhibitor CGS 14824A in normal volunteers.  |  Schaller, MD., et al. 1985. Eur J Clin Pharmacol. 28: 267-72. PMID: 2988972
  9. Decreased expression of transforming growth factor-β1 and α-smooth muscle actin contributes to the protection of lotensin against chronic renal failure in rats.  |  Xiao, Q., et al. 2018. Ren Fail. 40: 583-589. PMID: 30371125
  10. DELay of Appearance of sYmptoms of Canine Degenerative Mitral Valve Disease Treated with Spironolactone and Benazepril: the DELAY Study.  |  Borgarelli, M., et al. 2020. J Vet Cardiol. 27: 34-53. PMID: 32032923
  11. Comparison of Irbesartan and Benazepril Hydrochloride on Urine Protein Reduction in Chronic Glomerulonephritis.  |  Liu, Z., et al. 2020. J Coll Physicians Surg Pak. 30: 1000-1001. PMID: 33036695
  12. Clinical efficacy of a benazepril and spironolactone combination in dogs with congestive heart failure due to myxomatous mitral valve disease: The BEnazepril Spironolactone STudy (BESST).  |  Coffman, M., et al. 2021. J Vet Intern Med. 35: 1673-1687. PMID: 34028078
  13. ACE inhibitors: review of four new agents.  |  Binder, SB. 1993. Am Fam Physician. 48: 851-7. PMID: 8213415
  14. Delayed onset of angioedema with angiotensin-converting enzyme inhibitors: case report and review of the literature.  |  O'Mara, NB. and O'Mara, EM. 1996. Pharmacotherapy. 16: 675-9. PMID: 8840375
  15. Angiotensin-Converting Enzyme Inhibitors  |  . 2012. Livertox: Clinical And Research Information On Drug-Induced Liver Injury.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Benazepril-d5, 1 mg

sc-217708
1 mg
$367.00