Molecular structure of Befunolol, CAS Number: 39552-01-7
Befunolol (CAS 39552-01-7)
Alternate Names:
1-[7-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-2-benzofuranyl]-ethanone;(±)-Befunolol; 2-Acetyl-7-(2-hydroxy-3-isopropylaminopropoxy)benzofuran
CAS Number:
39552-01-7
Molecular Weight:
291.34
Molecular Formula:
C16H21NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Befunolol is a member of benzofurans It acts as a beta-adrenergic blocker and exhibits intrinsic sympathomimetic activity. However, it can also function as a partial agonist of beta-adrenergic receptors in isolated organs. In materials science, the structural features of befunolol could be utilized to design polymers or coatings with specific characteristics. For example, incorporating molecular structures similar to befunolol might influence the thermal stability, elasticity, or durability of materials.
Befunolol (CAS 39552-01-7) References
- Effects of the R(+)- and S(-)-isomers of beta-adrenoceptor blockers with intrinsic sympathomimetic activity, befunolol and carteolol, on rabbit intraocular pressure. | Takayanagi, I., et al. 1991. Can J Physiol Pharmacol. 69: 1243-5. PMID: 1685941
- Metabolic profile of beta-adrenoceptor-blocking action of befunolol. | Maruyama, Y., et al. 1991. Arch Int Pharmacodyn Ther. 311: 73-88. PMID: 1686392
- Protective effects of befunolol on hypoxic respiration-induced alterations in myocardial energy metabolism of rats. | Maruyama, Y., et al. 1991. Arzneimittelforschung. 41: 1022-6. PMID: 1799378
- Thermodynamic analysis of beta-adrenergic partial agonists (befunolol and carteolol) interaction with low and high affinity binding sites of beta-adrenoceptors in guinea-pig taenia caecum. | Takayanagi, I., et al. 1990. Gen Pharmacol. 21: 303-7. PMID: 1971246
- Kinetics of befunolol reductase from rabbit liver. | Nozaki, Y., et al. 1990. Chem Pharm Bull (Tokyo). 38: 156-8. PMID: 2186874
- Opacification test by using the pig isolated cornea and its application to a test of corneal opacity induced by befunolol hydrochloride. | Igarashi, H., et al. 1989. J Toxicol Sci. 14: 91-103. PMID: 2570879
- Interactions of R(+) and S(-) isomers of befunolol, a partial agonist with high and low affinity sites of beta-adrenoceptors in guinea-pig taenia caecum. | Takayanagi, I., et al. 1989. Arch Int Pharmacodyn Ther. 300: 76-84. PMID: 2575890
- Purification and characterization of befunolol reductase from rabbit liver. | Imamura, Y., et al. 1989. Chem Pharm Bull (Tokyo). 37: 3338-42. PMID: 2698771
- A derivative of befunolol, BFE-55, interacts with only the high affinity sites in beta-adrenoceptors. | Koike, K., et al. 1987. Can J Physiol Pharmacol. 65: 2150-3. PMID: 2827874
- A beta-adrenoceptor blocking agent, befunolol as a partial agonist in isolated organs. | Takayanagi, I. and Koike, K. 1985. Gen Pharmacol. 16: 265-7. PMID: 2862092
- A beta-adrenergic partial agonist (befunolol) discriminates two different affinity sites. | Koike, K. and Takayanagi, I. 1986. Jpn J Pharmacol. 42: 325-8. PMID: 2879061
- Enzyme immunoassays for beta-adrenoreceptor blocking agent, befunolol and its main metabolite, M1. | Sato, S. and Yamamoto, I. 1983. J Immunoassay. 4: 351-71. PMID: 6142059
- Comparison of interactions of R(+)- and S(-)-isomers of beta-adrenergic partial agonists, befunolol and carteolol, with high affinity site of beta-adrenoceptors in the microsomal fractions from guinea-pig ciliary body, right atria and trachea. | Koike, K., et al. 1994. Gen Pharmacol. 25: 1477-81. PMID: 7896063
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Befunolol, 25 mg | sc-503296 | 25 mg | $394.00 |