Molecular structure of Beclomethasone 17-propionate, CAS Number: 5534-18-9
Beclomethasone 17-propionate (CAS 5534-18-9)
Alternate Names:
(11β,16β)-9-Chloro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)-pregna-1,4-diene-3,20-dione; Beclomethasone 17-Monopropionate
Application:
Beclomethasone 17-propionate is an active metabolite of Beclomethasone dipropionate (BDP)
CAS Number:
5534-18-9
Molecular Weight:
464.98
Molecular Formula:
C25H33ClO6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Beclomethasone 17-Propionate is incorporated into research studies that focus on its anti-inflammatory properties, especially concerning its actions at the cellular and molecular levels. It is used in the examination of gene expression modulation, particularly targeting genes involved in inflammatory pathways. Researchers also study Beclomethasone 17-Propionate′s role in the regulation of cytokines and chemokines, as these are significant mediators in inflammatory responses. Moreover, the compound is of interest in the investigation of its effects on various immune cells, including its influence on cell signaling cascades that govern the immune response. In addition, Beclomethasone 17-Propionate serves as a useful tool in the study of airway inflammation mechanisms, providing insights into the inflammatory processes that occur in respiratory tissues.
Beclomethasone 17-propionate (CAS 5534-18-9) References
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- Simultaneous quantification of beclomethasone dipropionate and its metabolite, beclomethasone 17-monopropionate in rat and human plasma and different rat tissues by liquid chromatography-positive electrospray ionization tandem mass spectrometry. | Wang, Y. and Hochhaus, G. 2004. J Chromatogr B Analyt Technol Biomed Life Sci. 805: 203-10. PMID: 15135091
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- Formoterol counteracts the inhibitory effect of cigarette smoke on glucocorticoid-induced leucine zipper (GILZ) transactivation in human bronchial smooth muscle cells. | Marchini, G., et al. 2019. Eur J Pharmacol. 850: 8-14. PMID: 30753866
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- Determination of 43 prohibited glucocorticoids in cosmetic products using a simultaneous LC-MS/MS method | Nam Sook Kim,†a Geum Joo Yoo, †a Ji Hyun Lee,a Hyoung-Joon Park,a Sooyeul Cho,b Dong Woo Shin,a Younglim Kimc and Sun Young Baek*. 2017. Analytical Methods.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Beclomethasone 17-propionate, 1 mg | sc-207317 | 1 mg | $393.00 |