Molecular structure of Bcr-abl Inhibitor II, CAS Number: 607702-99-8
Bcr-abl Inhibitor II (CAS 607702-99-8)
Alternate Names:
4-fluoro-N-{5-[(4-fluorobenzyl)sulfanyl]-1,3,4-thiadiazol-2-yl}benzamide
Application:
Bcr-abl Inhibitor II is an inhibitor of c-Abl and SRC kinases
CAS Number:
607702-99-8
Purity:
≥97%
Molecular Weight:
363.40
Molecular Formula:
C16H11F2N3OS2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Bcr-abl Inhibitor II is a cell-permeable thiadiazole compound that acts as an ATP binding site-targeting inhibitor of c-Abl and SRC kinases (Ki = 44 and 354 nM, respectively). Bcr-abl Inhibitor II effectively inhibits cellular Bcr-abl Tyr245 phosphorylation and the clonogenic activity of Bcr-abl-transformed 32D cells, regardless of their resistance to Imatinib/STI571.
Inhibitor of:
c-Abl, and c-Src.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bcr-abl Inhibitor II, 5 mg | sc-221289 | 5 mg | $285.00 |