Bcl-2 Antibody (N-19): sc-492
- Bcl-2 Antibody (N-19) is a rabbit polyclonal IgG; 200 µg/ml; or goat IgG; 200 µg/ml, sc-492-G
- epitope mapping at the N-terminus of Bcl-2 of human origin
- Discontinued polyclonal antibody
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Bcl-2 is one among many key regulators of apoptosis, which are essential for proper development, tissue homeostasis, and protection against foreign pathogens. Human Bcl-2 is an anti-apoptotic, membrane-associated oncoprotein that can promote cell survival through protein-protein interactions with other Bcl-2 related family members, such as the death suppressors Bcl-xL, Mcl-1, Bcl-w, and A1 or the death agonists Bax, Bak, Bik, Bad, and Bid. The anti-apoptotic function of Bcl-2 can also be regulated through proteolytic processing and phospho-rylation. Bcl-2 may promote cell survival by interfering with the activation of the cytochrome c/Apaf-1 pathway through stabilization of the mitochondrial membrane. Mutations in the Bcl-2 gene can contribute to cancers where normal physiological cell death mechanisms are compromised by deregulation of the anti-apoptotic influence of Bcl-2.
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Contains Mercury: All HRP conjugates (including bundle forms) contain thiomersal, a mercury compound. Do not dispose in trash. Dispose as hazardous chemical waste according to local, state and federal regulations.
Download thiomersal SDS
Ordering Information
Bcl-2 (C-2): sc-7382 [ Recommended monoclonal replacement for Bcl-2 (N-19) ]
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bcl-2 Antibody (C-2) | sc-7382 | 200 µg/ml | $322.00 | |||
Bcl-2 Antibody (C-2): m-IgGκ BP-HRP Bundle | sc-520498 | 200 µg Ab, 40 µg BP | $361.00 | |||
Bcl-2 Antibody (C-2): m-IgG1 BP-HRP Bundle | sc-533466 | 200 µg Ab; 20 µg BP | $361.00 | |||
Bcl-2 Antibody (C-2) AC | sc-7382 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Bcl-2 Antibody (C-2) HRP | sc-7382 HRP | 200 µg/ml | $322.00 | |||
Bcl-2 Antibody (C-2) FITC | sc-7382 FITC | 200 µg/ml | $336.00 | |||
Bcl-2 Antibody (C-2) PE | sc-7382 PE | 200 µg/ml | $349.00 | |||
Bcl-2 Antibody (C-2) Alexa Fluor® 488 | sc-7382 AF488 | 200 µg/ml | $364.00 | |||
Bcl-2 Antibody (C-2) Alexa Fluor® 546 | sc-7382 AF546 | 200 µg/ml | $364.00 | |||
Bcl-2 Antibody (C-2) Alexa Fluor® 594 | sc-7382 AF594 | 200 µg/ml | $364.00 | |||
Bcl-2 Antibody (C-2) Alexa Fluor® 647 | sc-7382 AF647 | 200 µg/ml | $364.00 | |||
Bcl-2 Antibody (C-2) Alexa Fluor® 680 | sc-7382 AF680 | 200 µg/ml | $364.00 | |||
Bcl-2 Antibody (C-2) Alexa Fluor® 790 | sc-7382 AF790 | 200 µg/ml | $364.00 | |||
Bcl-2 Antibody (C-2) B | sc-7382 B | 200 µg/ml | $326.00 | |||
Bcl-2 Antibody (C-2) TRITC | sc-7382 TRITC | 200 µg/ml | $326.00 | |||
Bcl-2 Antibody (C-2) Alexa Fluor® 405 | sc-7382 AF405 | 200 µg/ml | $364.00 |