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Bathophenanthroline (CAS 1662-01-7)

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Alternate Names:
4,7-Diphenyl-1,10-phenanthroline, BPhen
Application:
Bathophenanthroline is a bidentate ligand for determination of iron
CAS Number:
1662-01-7
Purity:
≥98%
Molecular Weight:
332.40
Molecular Formula:
C24H16N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bathophenanthroline, a synthetic compound renowned for its unique properties, has become a vital component in scientific research. This phenanthroline derivative features a planar structure comprising a phenyl ring and two nitrogen atoms. Its versatility makes it highly valuable for biochemical and physiological studies, as it exhibits a remarkable ability to bind to diverse molecules. Functioning as a versatile ligand, bathophenanthroline engages with proteins, enzymes, and various other molecules. The binding process induces a conformational alteration within the protein or enzyme, consequently influencing its activity. This effect arises from the planar nature of bathophenanthroline, which has the capacity to induce conformational shifts in proteins or enzymes upon binding, leveraging its unique planar structure.


Bathophenanthroline (CAS 1662-01-7) References

  1. Modification of the selected method for the determination of serum iron. Substitution of bathophenanthroline by ferene S.  |  Charlier, C., et al. 1992. Ann Biol Clin (Paris). 50: 191-202. PMID: 1456498
  2. The effects of bathophenanthroline, bathophenanthrolinesulphonate and 2-thenoyltrifluoroacetone on mung-bean mitochondria and submitochondrial particles.  |  Rich, PR., et al. 1977. Biochem J. 162: 205-8. PMID: 192210
  3. Enhancement of electroluminescence in zirconium poly carboxylic acid-based light emitting diodes by bathophenanthroline ligand.  |  Shahroosvand, H., et al. 2013. Phys Chem Chem Phys. 15: 9899-906. PMID: 23677438
  4. Inhibition of the mitochondrial F1-ATPase by rose bengal mediated photooxidation. Interaction of the Fe2+ chelate of bathophenanthroline with the sensitizer.  |  Glaser, E., et al. 1988. Acta Chem Scand B. 42: 175-82. PMID: 2899936
  5. Low density lipoprotein oxidation by ferritin at lysosomal pH.  |  Ojo, OO. and Leake, DS. 2018. Chem Phys Lipids. 217: 51-57. PMID: 30287220
  6. A general platform for antibody purification utilizing engineered-micelles.  |  Dhandapani, G., et al. 2019. MAbs. 11: 583-592. PMID: 30618334
  7. An anticancer Os(II) bathophenanthroline complex as a human breast cancer stem cell-selective, mammosphere potent agent that kills cells by necroptosis.  |  Novohradsky, V., et al. 2019. Sci Rep. 9: 13327. PMID: 31527683
  8. Homogeneous Photocatalytic H2 Production Using a RuII Bathophenanthroline Metal-to-Ligand Charge-Transfer Photosensitizer.  |  Khnayzer, RS., et al. 2016. Chempluschem. 81: 1090-1097. PMID: 31964088
  9. N,N-Dimethylformamide-stabilised palladium nanoparticles combined with bathophenanthroline as catalyst for transfer vinylation of alcohols from vinyl ether.  |  Tabaru, K., et al. 2021. Org Biomol Chem. 19: 3384-3388. PMID: 33899901
  10. Purification of antibody fragments via interaction with detergent micellar aggregates.  |  Dhandapani, G., et al. 2021. Sci Rep. 11: 11697. PMID: 34083598
  11. New microfluidic paper-based analytical device for iron determination in urine samples.  |  Ferreira, FTSM., et al. 2021. Anal Bioanal Chem. 413: 7463-7472. PMID: 34654951
  12. Nanoparticle-Based Liquid-Liquid Extraction for the Determination of Metal Ions.  |  Sodia, TZ., et al. 2021. ACS Sens. 6: 4408-4416. PMID: 34793121
  13. Copper(II) cation and bathophenanthroline coordination enhance therapeutic effects of naringenin against lung tumor cells.  |  Caro-Ramírez, JY., et al. 2022. Biometals. 35: 1059-1076. PMID: 35931942
  14. The effect of bathophenanthroline and hydroxylamine on Mg2+-dependent ATPase in human erythrocytes.  |  Mircevová, L. and Simonová, A. 1974. Enzyme. 17: 160-7. PMID: 4275954
  15. Uncoupler-reversible inhibition of mitochondrial ATPase by metal chelates of bathophenanthroline. I. General features.  |  Carlsson, C. and Ernster, L. 1981. Biochim Biophys Acta. 638: 345-57. PMID: 6459123

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bathophenanthroline, 500 mg

sc-254953
500 mg
$55.00

Bathophenanthroline, 1 g

sc-254953A
1 g
$92.00