Molecular structure of Bassianolide
Bassianolide (CAS 64763-82-2)
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Application:
Bassianolide is an insecticidal reagent
CAS Number:
64763-82-2
Molecular Weight:
909.20
Molecular Formula:
C48H84N4O12
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Bassianolide is a cyclooctadepsipeptide insecticide isolated from the entomopathogenic fungi, Beauveria and Verticillium lecanii, first reported by researchers at University of Tokyo in 1978. Bassianolide is related to the insecticidal and nematocidal actives, PF1022 complex and the synthetic anthelminthic emodepside. While the mode of action of bassianolide is not fully resolved, it is thought to act on ion channels at the level of the neuromuscular junction, like emodepside. Bassianolide is one of the active components of Beauveria bassiana biocontrol products.
Bassianolide (CAS 64763-82-2) References
- Identification of the nonribosomal peptide synthetase gene responsible for bassianolide synthesis in wood-decaying fungus Xylaria sp. BCC1067. | Jirakkakul, J., et al. 2008. Microbiology (Reading). 154: 995-1006. PMID: 18375793
- Combinatorial mutasynthesis of scrambled beauvericins, cyclooligomer depsipeptide cell migration inhibitors from Beauveria bassiana. | Xu, Y., et al. 2009. Chembiochem. 10: 345-54. PMID: 19105175
- Biosynthesis of the cyclooligomer depsipeptide bassianolide, an insecticidal virulence factor of Beauveria bassiana. | Xu, Y., et al. 2009. Fungal Genet Biol. 46: 353-64. PMID: 19285149
- Engineered production of fungal anticancer cyclooligomer depsipeptides in Saccharomyces cerevisiae. | Yu, D., et al. 2013. Metab Eng. 18: 60-8. PMID: 23608474
- Cuticle-degrading proteases and toxins as virulence markers of Beauveria bassiana (Balsamo) Vuillemin. | Cito, A., et al. 2016. J Basic Microbiol. 56: 941-8. PMID: 27198125
- The Stress-Responsive and Host-Oriented Role of Nonribosomal Peptide Synthetases in an Entomopathogenic Fungus, Beauveria bassiana. | Liu, H., et al. 2017. J Microbiol Biotechnol. 27: 439-449. PMID: 27840396
- Aspergillus niger is a superior expression host for the production of bioactive fungal cyclodepsipeptides. | Boecker, S., et al. 2018. Fungal Biol Biotechnol. 5: 4. PMID: 29507740
- Investigation and molecular docking studies of Bassianolide from Lecanicillium lecanii against Plutella xylostella (Lepidoptera: Plutellidae). | Ravindran, K., et al. 2018. Comp Biochem Physiol C Toxicol Pharmacol. 206-207: 65-72. PMID: 29551387
- Cyclic Octamer Peptoids: Simplified Isosters of Bioactive Fungal Cyclodepsipeptides. | D'Amato, A., et al. 2018. Molecules. 23: PMID: 30029532
- Modified substrate specificity of a methyltransferase domain by protein insertion into an adenylation domain of the bassianolide synthetase. | Xu, F., et al. 2019. J Biol Eng. 13: 65. PMID: 31388353
- Characterization of mycotoxins from entomopathogenic fungi (Cordyceps fumosorosea) and their toxic effects to the development of asian citrus psyllid reared on healthy and diseased citrus plants. | Qasim, M., et al. 2020. Toxicon. 188: 39-47. PMID: 33058930
- Sarocladium and Lecanicillium Associated with Maize Seeds and Their Potential to Form Selected Secondary Metabolites. | Błaszczyk, L., et al. 2021. Biomolecules. 11: PMID: 33451141
- Metabolomic Analysis Demonstrates the Impacts of Polyketide Synthases PKS14 and PKS15 on the Production of Beauvericins, Bassianolide, Enniatin A, and Ferricrocin in Entomopathogen Beauveria bassiana. | Toopaang, W., et al. 2023. Metabolites. 13: PMID: 36984865
- On the inhibitory mechanism of bassianolide, a cyclodepsipeptide, in acetylcholine-induced contraction in guinea-pig taenia coli. | Nakajyo, S., et al. 1983. Jpn J Pharmacol. 33: 573-82. PMID: 6620728
- Inhibitory effect of bassianolide, a cyclodepsipeptide, on drug-induced contractions of isolated smooth muscle preparations. | Nakajyo, S., et al. 1982. Jpn J Pharmacol. 32: 55-64. PMID: 6953262
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bassianolide, 0.5 mg | sc-397290 | 0.5 mg | $426.00 |