BAPTA-tetracesium Salt (CAS 480436-84-8)

BAPTA-tetracesium salt (BAPTA-TC) is a compound extensively utilized in scientific research due to its broad range of applications and its ability to effectively bind to calcium ions. Derived from the chemical BAPTA (1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid), which was initially synthesized in the 1970s, BAPTA-tetracesium Salt functions as a chelating agent employed to bind and modulate calcium concentrations within cells. The versatility of BAPTA-tetracesium salt is evident in its utilization for various purposes. It allows for the modification of cellular calcium concentrations, facilitating the examination of calcium′s impact on cellular processes. Furthermore, it has been employed in drug development studies to modulate the effects of drugs on cells. BAPTA-tetracesium salt has also served as useful in investigating calcium′s effects on neuronal excitability, muscle contraction, and intracellular signaling pathways. By binding to calcium ions, BAPTA-tetracesium salt hinders their interaction with other molecules such as proteins and enzymes. Consequently, it prevents the activation of calcium-dependent cellular processes, including muscle contraction and neuronal excitability. Moreover, BAPTA-tetracesium salt′s binding to calcium ions impedes the activation of intracellular signaling pathways, facilitating the study of calcium′s influence on cellular mechanisms.