BAIAP2L1 Antibody (A-14): sc-100680
- BAIAP2L1 Antibody (A-14) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 100 µg/ml
- raised against recombinant BAIAP2L1 of human origin
- recommended for detection of BAIAP2L1 of human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for BAIAP2L1 Antibody (A-14). This work is in progress.
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BAIAP2L1 Antibody (A-14) is a mouse monoclonal IgG1 antibody that detects BAIAP2L1 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). BAIAP2L1, also known as insulin receptor tyrosine kinase substrate (IRTKS), is a 511 amino acid protein predominantly expressed in the liver, testis, bladder, lung, and heart, playing a crucial role in cellular dynamics. BAIAP2L1 contains an IMD (IRSp53/MTSS1 homology) domain, an SH3 domain, and a C-terminal region resembling a WH2 domain, which are essential for function in actin filament organization. BAIAP2L1 is involved in the formation of short actin clusters at the cell periphery, contrasting with the filopodia-like protrusions induced by IRSp53. BAIAP2L1 binds Rac through its N-terminal IMD domain, highlighting significance in cytoskeletal rearrangements and cellular signaling pathways. BAIAP2L1 is a substrate for the insulin receptor, undergoing tyrosine phosphorylation upon insulin stimulation, which underscores importance in metabolic regulation and cellular responses to growth factors. Anti-BAIAP2L1 antibody (A-14) serves as an invaluable tool for researchers studying actin dynamics and insulin signaling in human tissues.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BAIAP2L1 Antibody (A-14) | sc-100680 | 100 µg/ml | $339.00 |