Baclofen-d4 (CAS 1189938-30-4)

Baclofen-d4 is a deuterated form of the compound baclofen, used primarily in research to distinguish it from its non-deuterated analog in various analytical techniques. In scientific studies, baclofen-d4 is employed as an internal standard for mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy, providing a means of quantifying baclofen by exploiting the differences in mass or magnetic properties imparted by the presence of deuterium atoms. The use of baclofen-d4 allows for greater precision and accuracy in the detection and measurement of baclofen in complex biological matrices. Additionally, this compound is utilized in kinetic studies to track the absorption, distribution, metabolism, and excretion of baclofen, as the deuterated compound behaves similarly to the non-deuterated form in biological systems, but can be readily distinguished analytically. The incorporation of deuterium atoms into baclofen does not significantly alter its chemical properties, making baclofen-d4 an ideal tracer or marker in chemical and biochemical research.