Bacillus anthracis spore antigen Antibody (SA26): sc-51876

Bacillus anthracis spore antigen Antibody (SA26) is a mouse monoclonal IgG2a antibody that detects Bacillus anthracis spore antigen of Bacillus anthracis origin by western blotting (WB). Bacillus anthracis spore antigen (SA26) antibody is available in a non-conjugated form, providing researchers with a versatile tool for studying this critical protein. Bacillus anthracis spore antigen plays a vital role in pathogenicity, as this protein is a key component of the bacterium′s protective capsule, composed of poly-D-glutamic acid. This capsule is crucial for bacterial survival in hostile environments by preventing phagocytosis and evading host immune response. Bacillus anthracis spores remain dormant in the environment for extended periods and resist extreme conditions, underscoring the importance of understanding Bacillus anthracis spore antigen in anthrax infection. Anti-Bacillus anthracis spore antigen antibody (SA26) enables researchers to gain insights into virulence mechanisms and develop effective therapeutic strategies against anthrax.

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Bacillus anthracis spore antigen Antibody (SA26) References:

1. Definitive identification of Bacillus anthracis--a review.  |  Turnbull, PC. 1999. J Appl Microbiol. 87: 237-40. PMID: 10475956
2. Attenuated nontoxinogenic and nonencapsulated recombinant Bacillus anthracis spore vaccines protect against anthrax.  |  Cohen, S., et al. 2000. Infect Immun. 68: 4549-58. PMID: 10899854
3. Anthrax.  |  Mock, M. and Fouet, A. 2001. Annu Rev Microbiol. 55: 647-71. PMID: 11544370
4. Surface layer protein EA1 is not a component of Bacillus anthracis spores but is a persistent contaminant in spore preparations.  |  Williams, DD. and Turnbough, CL. 2004. J Bacteriol. 186: 566-9. PMID: 14702325
5. Bacillus anthracis toxins inhibit human neutrophil NADPH oxidase activity.  |  Crawford, MA., et al. 2006. J Immunol. 176: 7557-65. PMID: 16751402
6. Selection and evaluation of the immunogenicity of protective antigen mutants as anthrax vaccine candidates.  |  Yan, M., et al. 2008. Vaccine. 26: 947-55. PMID: 18192092
7. The ecology of anthrax spores: tough but not invincible.  |  Dragon, DC. and Rennie, RP. 1995. Can Vet J. 36: 295-301. PMID: 7773917
8. Internalization of a Bacillus anthracis protective antigen-c-Myc fusion protein mediated by cell surface anti-c-Myc antibodies.  |  Varughese, M., et al. 1998. Mol Med. 4: 87-95. PMID: 9508786
9. High-level expression and single-step purification of recombinant Bacillus anthracis protective antigen from Escherichia coli.  |  Lu, J., et al. 2009. Biotechnol Appl Biochem. 52: 107-12. PMID: 18416696

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Bacillus anthracis spore antigen Antibody (SA26) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Bacillus anthracis spore antigen Antibody (SA26) Specifications

Alternate Product Name: Bacillus anthracis spore antigen

Product Clone Name: SA26

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a

Amino Acids:

Epitope Target: Bacillus anthracis spore antigen

Epitope Species: Bacillus anthracis

Product Reactivity/Detection: Bacillus anthracis spore antigen

Species Reactivity/Detection: Bacillus anthracis

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB

Vialing Information: Each vial contains 100 µg IgG_2a in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Bacillus anthracis spore antigen Antibody (SA26): N/A