B Cell Marker Antibody (BB6-10A10): sc-52445

B Cell Marker Antibody (BB6-10A10) is a mouse monoclonal IgM antibody that detects the B Cell Marker protein of porcine origin by immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). B Cell Marker Antibody (BB6-10A10) is available in both non-conjugated and various conjugated forms, including phycoerythrin (PE) and fluorescein isothiocyanate (FITC). B cells are crucial components of the adaptive immune system, primarily responsible for the humoral immune response, which is vital for the production of antibodies that neutralize pathogens. B Cell Marker protein, specifically the B cell receptor (BCR), is a membrane-bound immunoglobulin that plays a pivotal role in B cell activation and differentiation. Each B cell expresses a unique BCR that recognizes a specific antigen, allowing for a tailored immune response. BCRs on the surface of B cells serve as a key marker for identifying and isolating these cells in various biological samples, making B Cell Marker (BB6-10A10) antibody an essential tool for researchers studying immune responses, B cell development, and related disorders in porcine models.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

B Cell Marker Antibody (BB6-10A10) References:

1. Hodgkin's disease expressing follicular dendritic cell marker CD21 without any other B-cell marker: a clinicopathologic study of nine cases.  |  Nakamura, S., et al. 1999. Am J Surg Pathol. 23: 363-76. PMID: 10199466
2. CD27: a memory B-cell marker.  |  Agematsu, K., et al. 2000. Immunol Today. 21: 204-6. PMID: 10782048
3. Presence of the d8/17 B-cell marker in children with rheumatic fever in Israel.  |  Harel, L., et al. 2002. Clin Genet. 61: 293-8. PMID: 12030895
4. Use of a B cell marker (B220) to discriminate between allergens and irritants in the local lymph node assay.  |  Gerberick, GF., et al. 2002. Toxicol Sci. 68: 420-8. PMID: 12151637
5. The value of anti-pax-5 immunostaining in routinely fixed and paraffin-embedded sections: a novel pan pre-B and B-cell marker.  |  Torlakovic, E., et al. 2002. Am J Surg Pathol. 26: 1343-50. PMID: 12360049
6. Human B cells express a CD45 isoform that is similar to murine B220 and is downregulated with acquisition of the memory B-cell marker CD27.  |  Bleesing, JJ. and Fleisher, TA. 2003. Cytometry B Clin Cytom. 51: 1-8. PMID: 12500291
7. B-cell marker negative (CD7+, CD19-) Epstein-Barr virus-related pyothorax-associated lymphoma with rearrangement in the JH gene.  |  Tomita, S., et al. 2003. Leuk Lymphoma. 44: 727-30. PMID: 12769353
8. Isolation and characterization of the B-cell marker CD20.  |  Ernst, JA., et al. 2005. Biochemistry. 44: 15150-8. PMID: 16285718
9. Monoclonal antibodies putatively identifying porcine B cells.  |  Denham, S., et al. 1998. Vet Immunol Immunopathol. 60: 317-28. PMID: 9589570

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-B Cell Marker Antibody (BB6-10A10) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-B Cell Marker Antibody (BB6-10A10) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

B Cell Marker Antibody (BB6-10A10) Specifications

Alternate Product Name: B Cell Marker

Product Clone Name: BB6-10A10

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM

Amino Acids:

Epitope Target: B Cell Marker

Epitope Species:

Product Reactivity/Detection: immature population of B cells in the follicles of ILPPs and a subpopulation of sIg low B cells in lymph nodes

Species Reactivity/Detection: porcine

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IP, IF, FCM

Vialing Information: Each vial contains 100 µg IgM in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for B Cell Marker Antibody (BB6-10A10): FITC: Fluoroscein, PE: Phycoerythrin