Azoxystrobin (CAS 131860-33-8)
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Azoxystrobin, a broad-spectrum fungicide belonging to the β-methoxyacrylate class, exhibits remarkable efficacy against a wide range of plant pathogens. It exerts its antifungal activity by specifically targeting mitochondrial respiration. By binding to the Qo site of the cytochrome bc1 complex, it effectively obstructs electron transfer. Although azoxystrobin possesses cytotoxic properties against MDA-kb2 cells (EC20 value: 2.9 µM), it does not exhibit any antiandrogenic activity. Structurally, azoxystrobin can be described as an aryloxypyrimidine compound with a 4,6-diphenoxypyrimidine skeleton. One of the phenyl rings carries a cyano group at C-2, while the other features a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also positioned at C-2. Functionally, it acts as an inhibitor of mitochondrial respiration by impeding electron transfer between cytochromes b and c1.
Azoxystrobin (CAS 131860-33-8) References
- Occurrence, fate and effects of azoxystrobin in aquatic ecosystems: a review. | Rodrigues, ET., et al. 2013. Environ Int. 53: 18-28. PMID: 23314040
- Determination of azoxystrobin and its impurity in pesticide formulations by liquid chromatography. | Marczewska, P., et al. 2020. J Environ Sci Health B. 55: 599-603. PMID: 32253976
- Respiratory Toxicity of Azoxystrobin, Pyraclostrobin and Coumoxystrobin on Chlorella vulgaris. | Wang, K., et al. 2020. Bull Environ Contam Toxicol. 104: 799-803. PMID: 32388572
- Ecotoxicity evaluation of azoxystrobin on Eisenia fetida in different soils. | Xu, Y., et al. 2021. Environ Res. 194: 110705. PMID: 33400946
- Behavior of acetamiprid, azoxystrobin, pyraclostrobin, and lambda-cyhalothrin in/on pomegranate tissues. | Mohapatra, S., et al. 2021. Environ Sci Pollut Res Int. 28: 27481-27492. PMID: 33506422
- Azoxystrobin amine: A novel azoxystrobin degradation product from Bacillus licheniformis strain TAB7. | Mpofu, E., et al. 2021. Chemosphere. 273: 129663. PMID: 33515965
- Azoxystrobin increases the infection of spring viraemia of carp virus in fish. | Liu, L., et al. 2021. Chemosphere. 285: 131465. PMID: 34329124
- Azoxystrobin Impairs Neuronal Migration and Induces ROS Dependent Apoptosis in Cortical Neurons. | Kang, J., et al. 2021. Int J Mol Sci. 22: PMID: 34830376
- Oral azoxystrobin driving the dynamic change in resistome by disturbing the stability of the gut microbiota of Enchytraeus crypticus. | Zhang, Q., et al. 2022. J Hazard Mater. 423: 127252. PMID: 34844364
- Uptake, Accumulation, and translocation of azoxystrobin by Vegetable plants in soils: influence of soil characteristics and plant species. | Xu, S., et al. 2022. Bull Environ Contam Toxicol. 109: 386-392. PMID: 35670838
- Azoxystrobin induces apoptosis via PI3K/AKT and MAPK signal pathways in oral leukoplakia progression. | Li, L., et al. 2022. Front Pharmacol. 13: 912084. PMID: 35991869
- Azoxystrobin exposure impairs meiotic maturation by disturbing spindle formation in mouse oocytes. | Gao, W., et al. 2022. Front Cell Dev Biol. 10: 1053654. PMID: 36531942
- Effect of azoxystrobin on tobacco leaf microbial composition and diversity. | Sun, M., et al. 2022. Front Plant Sci. 13: 1101039. PMID: 36816485
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Azoxystrobin, 25 mg | sc-364349A | 25 mg | $50.00 | |||
Azoxystrobin, 100 mg | sc-364349 | 100 mg | $152.00 | |||
Azoxystrobin, 500 mg | sc-364349B | 500 mg | $458.00 | |||
Azoxystrobin, 1 g | sc-364349C | 1 g | $848.00 |