Molecular structure of Azlocillin sodium salt, CAS Number: 37091-65-9
Azlocillin sodium salt (CAS 37091-65-9)
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Alternate Names:
D-α-([Imidazolidin-2-on-1-yl]carbonylamino)benzylpenicillin
Application:
Azlocillin sodium salt is a semisynthetic penicillin and is a potent 1-lactam antibiotic
CAS Number:
37091-65-9
Purity:
≥95%
Molecular Weight:
483.47
Molecular Formula:
C20H22N5O6SNa
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Azlocillin sodium salt is a penicillin derivative and a broad-spectrum antibiotic. For example, it is active against a variety of Gram-positive and Gram-negative bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, and Klebsiella pneumoniae. It works by binding to penicillin-binding proteins (PBPs) in bacterial cells. This binding inhibits the synthesis of the bacterial cell wall, leading to cell death. Azlocillin sodium salt can be used against Pseudomonas aeruginosa and has been used to develop novel antibiotic quantitation techniques. Its antimicrobial activity, Azlocillin sodium salt has anti-inflammatory, anti-angiogenic, and immunomodulatory effects.
Azlocillin sodium salt (CAS 37091-65-9) References
- Large-Scale Phenotype-Based Antiepileptic Drug Screening in a Zebrafish Model of Dravet Syndrome. | Dinday, MT. and Baraban, SC. 2015. eNeuro. 2: PMID: 26465006
- Identification of new drug candidates against Borrelia burgdorferi using high-throughput screening. | Pothineni, VR., et al. 2016. Drug Des Devel Ther. 10: 1307-22. PMID: 27103785
- Enhanced antibacterial effect of azlocillin in conjugation with silver nanoparticles against Pseudomonas aeruginosa. | Alizadeh, A., et al. 2017. IET Nanobiotechnol. 11: 942-947. PMID: 29155393
- Antimicrobial and Antibiofilm Activity of Synergistic Combinations of a Commercially Available Small Compound Library With Colistin Against Pseudomonas aeruginosa. | Torres, NS., et al. 2018. Front Microbiol. 9: 2541. PMID: 30410476
- Novel Findings of Anti-Filarial Drug Target and Structure-Based Virtual Screening for Drug Discovery. | Choi, TW., et al. 2018. Int J Mol Sci. 19: PMID: 30428563
- Azlocillin can be the potential drug candidate against drug-tolerant Borrelia burgdorferi sensu stricto JLB31. | Pothineni, VR., et al. 2020. Sci Rep. 10: 3798. PMID: 32123189
- Optimization of a High-Throughput 384-Well Plate-Based Screening Platform with Staphylococcus aureus ATCC 25923 and Pseudomonas aeruginosa ATCC 15442 Biofilms. | Gilbert-Girard, S., et al. 2020. Int J Mol Sci. 21: PMID: 32344836
- Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay. | Zink, A., et al. 2020. Front Cell Dev Biol. 8: 590540. PMID: 33224955
- Screening of an FDA-Approved Library for Novel Drugs against Y. pestis. | Gur, D., et al. 2021. Antibiotics (Basel). 10: PMID: 33401634
- FDA-Approved Drug Screening for Compounds That Facilitate Hematopoietic Stem and Progenitor Cells (HSPCs) Expansion in Zebrafish. | Feng, Z., et al. 2021. Cells. 10: PMID: 34440919
- Predictive Model for Drug-Induced Liver Injury Using Deep Neural Networks Based on Substructure Space. | Kang, MG. and Kang, NS. 2021. Molecules. 26: PMID: 34946636
- Cyclic di-AMP as endogenous adjuvant enhanced BCG-induced trained immunity and protection against Mycobacterium tuberculosis in mice. | Ning, H., et al. 2022. Front Immunol. 13: 943667. PMID: 36081510
- Cheminformatics Study on Structural and Bactericidal Activity of Latest Generation β-Lactams on Widespread Pathogens. | Gherman, AMR., et al. 2022. Int J Mol Sci. 23: PMID: 36293563
- Evidence for Complex Interplay between Quorum Sensing and Antibiotic Resistance in Pseudomonas aeruginosa. | Sikdar, R. and Elias, MH. 2022. Microbiol Spectr. 10: e0126922. PMID: 36314960
- Stability study of azlocillin sodium in glass bottles and PVC bags containing intravenous admixtures. | Puiggròs Boldú, S., et al. 1995. Boll Chim Farm. 134: 467-71. PMID: 7576447
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Enzyme.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Azlocillin sodium salt, 1 g | sc-254950 | 1 g | $101.00 |