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Azido-PEG3-amine (CAS 134179-38-7)

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Alternate Names:
2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethylamine; 11-Azido-3,6,9-trioxaundecan-1-amine
Application:
Azido-PEG3-amine is a PEG derivative used as a bifunctional, hydrophilic linker
CAS Number:
134179-38-7
Purity:
≥93%
Molecular Weight:
218.25
Molecular Formula:
C8H18N4O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Azido-PEG3-amine is a chemical compound characterized by its unique structure that includes amino and azido functional groups, along with a polyether backbone. The azido group provides a reactive site for click chemistry reactions, a method used to join small units together with high specificity and reliability under mild conditions. The amino group allows for further functionalization or conjugation, enhancing its utility in synthesizing complex molecules. The polyether part of the molecule increases solubility in various solvents, making it versatile for different chemical synthesis applications.


Azido-PEG3-amine (CAS 134179-38-7) References

  1. Convergent assembly and surface modification of multifunctional dendrimers by three consecutive click reactions.  |  Ledin, PA., et al. 2011. Chemistry. 17: 839-46. PMID: 21226098
  2. A novel pyrene-based fluorescing amphiphile with unusual bulk and interfacial properties.  |  Salonen, A., et al. 2011. Chemphyschem. 12: 150-60. PMID: 21226196
  3. Oligonucleotide tagging for copper-free click conjugation.  |  Jawalekar, AM., et al. 2013. Molecules. 18: 7346-63. PMID: 23884112
  4. Preparation and in vitro photodynamic activities of folate-conjugated distyryl boron dipyrromethene based photosensitizers.  |  Ke, MR., et al. 2013. J Med Chem. 56: 8475-83. PMID: 24088087
  5. Transglutaminase-based chemo-enzymatic conjugation approach yields homogeneous antibody-drug conjugates.  |  Dennler, P., et al. 2014. Bioconjug Chem. 25: 569-78. PMID: 24483299
  6. Dual-modal MRI contrast agent with aggregation-induced emission characteristic for liver specific imaging with long circulation lifetime.  |  Chen, Y., et al. 2014. ACS Appl Mater Interfaces. 6: 10783-91. PMID: 24942209
  7. Cytocompatible in situ forming chitosan/hyaluronan hydrogels via a metal-free click chemistry for soft tissue engineering.  |  Fan, M., et al. 2015. Acta Biomater. 20: 60-68. PMID: 25839124
  8. Synthesis of non-natural sequence-encoded polymers using phosphoramidite chemistry.  |  Al Ouahabi, A., et al. 2015. J Am Chem Soc. 137: 5629-35. PMID: 25851514
  9. Injectable dextran hydrogels fabricated by metal-free click chemistry for cartilage tissue engineering.  |  Wang, X., et al. 2017. Mater Sci Eng C Mater Biol Appl. 73: 21-30. PMID: 28183600
  10. Synthesis of Diverse α-Fluoroalkoxyaryl Derivatives and Their Use for the Generation of Fluorinated Macrocycles.  |  Cogswell, TJ., et al. 2019. Chemistry. 25: 1184-1187. PMID: 30329185
  11. Molecular Dynamics of Functional Azide-Containing Acrylic Films.  |  Carsí, M., et al. 2018. Polymers (Basel). 10: PMID: 30960784
  12. An antibody-supermolecule conjugate for tumor-specific targeting of tumoricidal methylated β-cyclodextrin-threaded polyrotaxanes.  |  Nishida, K., et al. 2020. J Mater Chem B. 8: 6975-6987. PMID: 32573639
  13. Encoding hierarchical assembly pathways of proteins with DNA.  |  Hayes, OG., et al. 2021. Proc Natl Acad Sci U S A. 118: PMID: 34593642
  14. Manipulating Chemical Processes by Pseudosolid Spatial Limitation.  |  Yi, S., et al. 2021. JACS Au. 1: 1435-1444. PMID: 34604853

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Azido-PEG3-amine, 1 g

sc-208597
1 g
$390.00

I'd appreciate if you can help me with a compatibility question so I can determine what reactor should be used. Is Azido-PEG3-amine compatible with stainless steel and plastic? Thank you very much for your help.

Asked by: Lifecore
Thank you for your question. Unfortunately we do not have any information related to this type of compatibility with different container materials.
Answered by: Technical Support
Date published: 2017-11-03
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Rated 5 out of 5 by from Various publications cite the use of 1Various publications cite the use of 1-Amino-11-azido-3,6,9-trioxaundecane as a bifunctional, hydrophilic linker. -SCBT Publication Review
Date published: 2015-06-21
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Azido-PEG3-amine is rated 5.0 out of 5 by 1.
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