Molecular structure of Azelnidipine, CAS Number: 123524-52-7
Azelnidipine (CAS 123524-52-7)
Alternate Names:
2-Amino-1,4-dihydro-6-methyl-4-(3 nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[1-(diphenylmethyl)-3-azetidinyl] 5-(1-methylethyl) ester
Application:
Azelnidipine is an L-type calcium channel protein inhibitor
CAS Number:
123524-52-7
Purity:
≥99%
Molecular Weight:
582.65
Molecular Formula:
C33H34N4O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Azelnidipine is a novel dihydropyridine derivative, an L-type calcium channel protein inhibitor and an antihypertensive. Unlike other L-type calcium channel blockers, azelnidipine causes minimal stimulation of the sympathetic nervous system despite its significant depressor effect. Azelnidipine may have a protective role in inflammation in atherosclerosis.
Azelnidipine (CAS 123524-52-7) References
Nakamoto, M., et al., Azelnidipine attenuates cardiovascular and sympathetic responses to air-jet stress in genetically hypertensive rats. Hypertens. Res. 30, 359-366, (2007)Inhibitor of:
ACAT-3, Cacna2d4, Calcium Channel Protein, CALML3, L-type Ca++ CP α1C/1D/1F/1S, L-type Ca++ CP α1D, L-type Ca++ CP α1F, L-type Ca++ CP γ2, L-type Ca++ CP γ4, L-type calcium channel α1C, L-type calcium channel α1D, L-type calcium channel α1F, L-type calcium channel β1, L-type Calcium Channel γ, Olr408, SLC24A1, and THIK-2.Activator of:
1600002H07Rik, L-type calcium channel α1C, R-type calcium channel α1E, WCRF, and ZBTB3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Azelnidipine, 10 mg | sc-252395 | 10 mg | $86.00 |